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The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Alopecia areata's causes are unclear, treatments exist but relapses are common.

Testosterone is crucial for development, growth, and various body functions in mammals.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

COVID-19 may harm male fertility and damage the reproductive system.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Early diagnosis and treatment of TPP can prevent complications.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Spermidine helps protect against aging by preserving telomere length.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Topical vitamin D is effective in treating vitiligo with few side effects.

The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.