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research Mechanisms of Dermatophyte Invasion on New Zealand Rabbit Skin Models
In this study, an infection model using rabbits was developed for dermatophytosis by inoculating macroconidia of Microsporum species, showing that direct intradermal application effectively progressed to the skin invasion phase and highlighted the correlation between severity of symptoms and duration post-inoculation.
research Mechanically compliant multifunctional bioadhesive hydrogel for rapid wound repair
research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.
research Overcoming genetic drivers in alopecia areata: hair regrowth in a patient with AIRE gene mutation (autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, APECED syndrome) treated with ruxolitinib
In this case report, complete hair regrowth was observed in a patient with autoimmune-related alopecia areata after treatment with a Janus kinase inhibitor, suggesting its potential effectiveness for both genetic and sporadic forms of the condition.
research Comparative study of cutaneous manifestations in patients with chronic kidney disease , patients on haemodialysis, and renal transplant recipients
Skin problems are common in kidney disease, with dry skin and itching in patients not on dialysis or on hemodialysis, and infections most common in transplant recipients.
research Vitadetect : Vitamin Deficiency Detection
In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.
research 26 Characterization of a murine model of aa induced by adoptive transfer of cultured lymph node cells
In this study, researchers used a mouse model of alopecia areata to demonstrate that both ruxolitinib and baricitinib, oral JAK inhibitors, reduced hair loss, CD8+ cell infiltration, and expression of disease-related markers, with baricitinib showing greater effectiveness.
research A double blind, randomised, vehicle-controlled, safety and tolerance study of topical PSK 3841 solution at 5% administered twice daily over four weeks to healthy Caucasian males with androgenetic alopecia
research ANAPLASMOSIS IN KINTAMANI CROSSBREED DOG: A CASE REPORT
This case report describes successful treatment of anaplasmosis in a Kintamani mix dog with doxycycline, ivermectin, vetadryl, and Livron b-plex, leading to improved activity, hair growth, appetite, and tick eradication.
research A COMPARISON STUDY OF HAIR TONIC AND GEL FORMULATION OF ANGIOPTERIS EVECTA AS A HAIR GROWTH STIMULANT
This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
research First drug for severe alopecia recommended by NICE could benefit 14,000 patients
In this report, NICE has approved ritlecitinib, an oral kinase inhibitor, as the first recommended treatment for severe alopecia areata in individuals aged 12 and older.
research Baricitinib for alopecia areata
This source reports that clinical trials found oral baricitinib significantly improved hair regrowth in patients with severe alopecia areata, with 38.8% achieving at least 80% scalp hair coverage after 36 weeks on a 4-mg dose, compared to 6.2% with placebo in trial 1.
research UJI AKTIVITAS PERTUMBUHAN RAMBUT KELINCI JANTAN DARI SEDIAAN HAIR TONIC YANG MENGANDUNG EKSTRAK ETANOL DAUN MANGKOKAN (Nothopanax scutellarium L.)
In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
research BH08 Unprovoked pulmonary emboli in a patient with alopecia areata treated with ritlecitinib: a case report
This case report details a probable severe adverse event associated with ritlecitinib for alopecia areata, highlighting risks of pulmonary emboli, infection, atrial fibrillation, and acute kidney injury despite an absence of known risk factors.
research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization
In this paper, Chemistry42—a software integrating AI with computational and medicinal chemistry—demonstrated efficiency in designing novel molecular structures targeting DDR1 and CDK20, with properties validated in both in vitro and in vivo studies.
research 42736 Safety Assessments in the Multinational Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
CTP-543 is generally safe for treating alopecia areata.
research Business Analysis of Pomade Rambutan Leaf Extract with Apple Aroma Anti-Gray Hair and Multipurpose as a Green Economy Alternative
This study focused on developing a pomade called "Hyung Hair" made from rambutan leaf extract, which showed potential benefits such as reducing hair loss and slowing gray hair growth, with a feasibility analysis indicating the business's viability.
research Effects of Fumai Paste on EGFR of Skin in Vinorelbine-induced Extravasation Injury Model Rats
In this study, Fumai Paste was found to enhance EGFR expression and accelerate healing in a rat model of vinorelbine-induced skin injury more effectively than magnesium sulfate or saline treatments.
research Skin transcriptome reveals the periodic changes in genes underlying cashmere (ground hair) follicle transition in cashmere goats
This study observed that the growth cycle of cashmere in Inner Mongolian cashmere goats consists of three phases, with genes KAP3–1, KRTAP 8–1, and KRTAP 24–1 closely correlating with this cycle.
research Comparative Efficacy of Topical Calcipotriol, Intralesional Autologous Platelet-Rich Plasma Injection, and Combined Topical Calcipotriol with Intralesional Autologous Platelet-Rich Plasma Injection on Patients with Alopecia Areata
This study found that combining topical calcipotriol with intralesional autologous PRP injection significantly reduced Severity of Alopecia Tool scores in patients with alopecia areata, more effectively than either treatment alone.
research PLATELET RICH PLASMA THERAPY FOR SKIN REJUVENATION
This article discusses the popularity and mechanisms of Platelet Rich Plasma therapy for skin rejuvenation and hair loss, but it reports no new clinical results.
research A Brief Study Examining the Variability of PRP with Different Preparation Systems
This study observed significant variation in platelet concentrations across four different platelet-rich plasma (PRP) systems, suggesting that PRP system choice may affect treatment outcomes for hair growth.
research Population exposure–response analysis of the effect of ritlecitinib on eyebrow assessment and eyelash assessment in patients with alopecia areata
In this study, the researchers evaluated the exposure-response relationship of ritlecitinib on eyebrow and eyelash regrowth and concluded that the established models justify selecting a 50 mg dose for patients with severe alopecia areata, while highlighting differing efficacy among evaluation methods.
research Relapse of alopecia areata during ongoing Janus kinase inhibitor therapy is not uncommon and usually occurs in previously affected areas: A multicenter Italian real-world study
This abstract does not report results but indicates that the supplementary material includes comprehensive methodology, additional results, statistical analyses, discussion, and limitations of the Alopecia Areata Relapse Study Group's findings as presented in the main manuscript.
research Classification of Visually Similar Scalp Diseases using Deep Learning: A Hybrid CNN-VIT Approach with Cross-Attention Fusion
This study introduces ScalpViT, a new deep learning model that accurately diagnoses visually similar scalp diseases with 94.3% accuracy, outperforming other methods like ResNet-50 and EfficientNet-B3, and providing dual visual explainability through GradCAM and Attention Rollout, potentially benefiting diagnosis in resource-limited settings in India.
research Stem cell activity-coupled suppression of endogenous retrovirus governs adult tissue regeneration
research Hair Restoration
This article promotes a hair transplant clinic in Killeen City, Texas, and does not provide any research findings.
research Uji efek formulasi sediaan hair tonic perasan daun kacang panjang (vigna sinensis (l.) savi ex hassk) terhadap pertumbuhan rambut kelinci jantan
In this study, a hair tonic formulation with bean leaf juice increased hair growth in male rabbits, with concentration-dependent improvements in hair length and weight compared to a control.