research Screening 5α-Reductase Inhibitors from Plant Extraction for Treatment of Androgenic Alopecia In Vitro
Coffee extract and caffeotannic acid can help treat hair loss.
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research Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research Enhanced Skin Permeation of 5α-Reductase Inhibitors Entrapped into Surface-Modified Liquid Crystalline Nanoparticles
Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
research Clinicopathological Characteristics and Treatment Outcomes of Fibrosing Alopecia in a Pattern Distribution: A Retrospective Cohort Study
Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
![Patent Evaluation: Hexahydrobenzo[f]quinolines as 5α-Reductase Inhibitors](/images/research/1634373b-f615-46c7-a157-21394e3366be/small/21095.jpg)
research Patent Evaluation: Hexahydrobenzo[f]quinolines as 5α-Reductase Inhibitors
Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.
research Fibrosing Alopecia in a Pattern Distribution
FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
research Dihydrotestosterone And The Prostate: The Scientific Rationale For 5α-Reductase Inhibitors In The Treatment Of Benign Prostatic Hyperplasia
Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.
research Update on Frontal Fibrosing Alopecia
Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
research Frontal Fibrosing Alopecia: An Update on Epidemiology and Treatment
New treatments for Frontal Fibrosing Alopecia show promise, especially finasteride and dutasteride, with most patients seeing improvement or stabilization.
research The Role of Dietary Supplements in Hair Loss Treatment: A Review of Evidence
Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
research Risk of Age-Related Macular Degeneration in Men Receiving 5α-Reductase Inhibitors: A Population-Based Cohort Study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
research Differential Association Between Cumulative Dose of 5α-Reductase Inhibitors and Mortality
Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.
research What Is the Role of 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia? An Evidence-Based Review
5α-reductase inhibitors are effective for treating hair loss in androgenetic alopecia.
research Effect of Finasteride on Prostate-Specific Antigen
Finasteride significantly reduces PSA levels in men, and doctors should adjust PSA readings for those taking the drug.
research Inhibitors of 5α-Reductase Type I in LNCaP Cells from the Roots of Angelica Koreana
Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.
research A Systematic Review of Antiandrogens and Feminization in Transgender Women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research The Changing Landscape of Managing Hair Loss: A 30-Year Perspective
There have been major advances in diagnosing and treating hair loss over the last 30 years, with new drugs and improved hair transplant techniques.
research 5α-Reductase Inhibitors and Male Reproduction
5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
research Study on the Clinical Efficacy and Mechanism of Action of Dutasteride in Female-Pattern Hair Loss
Dutasteride effectively increases hair density in women with hair loss.
research Enzyme-Linked Immunosorbent Assays for Doping Control of 5α-Reductase Inhibitors Finasteride and Dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Guest Editorial: The Maturation of Hair Loss and Restoration Field
The editorial concludes that the field of hair loss treatment has become more scientific and that effective treatments are important for self-esteem and job prospects.
research An Update on the Treatment of Female Alopecia and the Introduction of a Potential Novel Therapy
Minoxidil is the only drug proven to improve female hair loss, and dextroamphetamine sulfate may be a new treatment for certain types of hair loss.
research Lack of Association Between 5α-Reductase Inhibitors and Depression
5α-Reductase inhibitors don't cause depression.
research Frontal Fibrosing Alopecia in Men: A Review of the Literature
Frontal fibrosing alopecia in men is often misdiagnosed and needs better diagnostic criteria and treatments.
research Association of Treatment with 5α-Reductase Inhibitors with Time to Diagnosis and Mortality in Prostate Cancer
Treatment with 5α-reductase inhibitors is linked to a delay in prostate cancer diagnosis and may affect survival rates.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Pharmacological Approaches in Managing Symptomatic Relief of Benign Prostatic Hyperplasia: A Comprehensive Review
Tadalafil is effective for treating urinary symptoms in men with BPH.
research Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review
Personalized treatments for hair loss are becoming more effective by using genetic information.
research In Vitro and In Vivo Effects of 17β-N-(4-Phenylcarbamoyl) Androst-4-en-3-one Derivatives as 5α-Reductase Inhibitors on Androgen-Dependent Glands
Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.