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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Nonionic liposomes are the best for delivering genes to skin cells.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Sub3 is essential for fungus adherence but not for skin invasion.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.