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Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

The document concludes that hair transplantation is recommended for those not helped by medical treatments, but warns that high-density transplants may lower hair survival rates.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.

Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

COVID-19 may cause early hair loss similar to classic temporary hair loss, with further research needed.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Combining electrodynamic microneedle with 5% minoxidil improves hair growth and reduces hair loss in Chinese men.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Thymosin β4 helps improve skin healing and reduce scarring.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Proteins from stem cells improved hair growth in patients with hair loss.

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.