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The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Reduced AR gene methylation may cause early pubic hair growth in girls.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Vertex pattern hair loss linked to higher prostate cancer risk.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

Signaling pathways are crucial for hair growth in goats.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Mutations in certain receptors can cause diseases and offer new treatment options.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Chemotherapy causes hair loss starting soon after treatment begins and recovers about 3 months after ending, while tamoxifen does not significantly affect hair growth.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

DHT stops hair regrowth in mice, similar to human hair loss.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Finasteride works better for baldness in people with shorter gene repeats.