131 citations,
May 2015 in “Experimental Dermatology” Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.
130 citations,
November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
130 citations,
January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
130 citations,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
129 citations,
November 2005 in “Internal Medicine Journal” Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
129 citations,
October 2000 in “British Journal of Dermatology” Finasteride helps increase hair growth in men with hair loss.
128 citations,
January 1996 in “Journal of analytical toxicology.” Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
127 citations,
March 2004 in “Gynecologic oncology” Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.
125 citations,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
122 citations,
November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
121 citations,
January 1991 in “Acta dermato-venereologica” Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
119 citations,
January 2012 in “Nutrition & Metabolism” Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
117 citations,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
115 citations,
September 2000 in “The Lancet” Early hair loss may indicate risk of insulin resistance.
113 citations,
July 2020 in “Communications biology” Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
111 citations,
November 2010 in “Human Reproduction” South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.
111 citations,
June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
110 citations,
January 2014 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
107 citations,
August 2014 in “Dermatologic Surgery” PRP injections improve hair thickness for baldness.
107 citations,
August 2002 in “Journal of Neurology, Neurosurgery, and Psychiatry” Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
105 citations,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
105 citations,
January 2009 in “Medicine” Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
104 citations,
January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
103 citations,
June 2006 in “British journal of sports medicine” The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
103 citations,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
102 citations,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.