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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Polymeric nanoparticles show promise for treating skin diseases.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Apoptosis is essential for human skin development and forming a functional epidermis.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.