research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
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research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Androgen Receptor: A Promising Therapeutic Target in Breast Cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Cognitive and Mood Side Effects of Lower Urinary Tract Medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research Stem Cell Rejuvenation and the Role of Autophagy in Age Retardation by Caloric Restriction: An Update
Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Relations Between Sex Hormone Levels and Characteristics of Hair and Skin in Healthy Young Men
Higher androgen levels do not cause baldness in men.
research Minoxidil Overdose With ECG Changes: Case Report and Review
Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
research Age-Dependent Associations Between Androgenetic Alopecia and Prostate Cancer Risk
Early balding at 40 increases prostate cancer risk.
research Expression of the SCUBE3 Epidermal Growth Factor-Related Gene During Early Embryonic Development in the Mouse
Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.
research The History of Hair Transplantation
Hair transplantation has evolved since 1822, with significant advancements by key figures and widespread international growth.
research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
research Menopausal Acne – Challenges And Solutions
Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Menstrual Cycle Alterations During Adolescence: Early Expression of Metabolic Syndrome and Polycystic Ovary Syndrome
Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.
research Cell and Tissue Damage After Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects After Single and Fractional Doses
Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research How Do We Investigate Hematuria and What Role Has Finasteride?
Finasteride can treat prostatic haematuria, but its use is controversial.
research Severe and Fatal Phenobarbitone Eruptions
Phenobarbitone can cause severe and sometimes fatal skin reactions.
research Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics
Tiny natural vesicles from cells might help treat hair loss.
research Early Embryonic Exposure of Freshwater Gastropods to Pharmaceutical 5-Alpha-Reductase Inhibitors Results in a Surprising Open-Coiled 'Banana-Shaped' Shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Successful White Hair Removal with Combined Coloring and Intense Pulsed Light: A Randomized Clinical Trial
Coloring white hair before IPL treatment effectively helps remove it.
research Androgenetic Alopecia: The Role of Inflammation and Demodex
Inflammation and Demodex mites might contribute to hair loss, and targeting them could help treat it.
research Thrombocytosis Associated with Low-Molecular-Weight Heparin
International medical graduates outperformed U.S. graduates on an internal medicine exam.
research Adult Group B Streptococcal Disease
International medical graduates outperformed U.S. graduates on an internal medicine exam.
research Rat Steroid 5α-Reductase Kinetic Characteristics: Extreme pH-Dependency of the Type II Isozyme in Prostate and Epididymis Homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo
Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.