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This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.

This study found that epidermal Wnt production is crucial for forming the skin's spinous layer through a BMP-FGF signaling cascade, although Wnt from basal cells is not needed for their differentiation.

This study suggests that the combination of bendamustine and rituximab is at least as effective and possibly offers a better therapeutic index than other standard regimens as first-line treatment for certain lymphoma patients.

In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.

This review discusses the use of CDK4/6 inhibitors with endocrine therapy in treating women with HR+ HER2- advanced breast cancer, but it reports no new clinical findings.

This study found that treatment with the polyphenolic compound TCQA activated β-catenin, promoting hair regrowth and the initiation of the anagen phase in mice and human dermal papilla cells.

In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.

This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.

This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.

This study found that Tianqi trichogen promoted hair growth in tested animals, with no observed photoallergic reactions or significant skin allergies.

This study found that Tinea Corporis significantly impacts the quality of life of patients, with disease duration and body surface area involved being key factors.

This study developed a high-throughput method that identifies bioactive chemicals influencing DHT production in prostate cancer cells, with potential nutraceutical candidates including fucoxanthin, phenethyl caffeate, and Curcuma longa L. extract.

This essay introduces Dr. Qiu's approach to treating consumptive syndromes with TCM after radio-chemotherapy, discussing how modern cancer treatments cause these symptoms and his unique perspective on their management.

This study found that CTCF is crucial for proper skin and hair follicle development in mice, affecting keratinocyte differentiation and gene expression in keratin loci.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.

In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.

This study found that patients taking hydroxychloroquine had a significantly higher likelihood of indeterminate QuantiFERON-TB Gold test results compared to those not on the medication, independent of other immunosuppressive drug use.

This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.

This study revealed distinct cellular and transcriptomic differences among various subtypes of cutaneous T-cell lymphoma, particularly highlighting characteristics unique to folliculotropic mycosis fungoides.

This study presents a validated questionnaire, the FFA-QLI, which effectively assesses and differentiates the quality of life impact among patients with frontal fibrosing alopecia, showing greater sensitivity in identifying severe cases than the DLQI.

In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.

In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.

This study demonstrated that in a mouse melanoma wound model, the MQ Microneedles effectively managed ROS levels to inhibit tumor growth and promote wound healing through light-controlled release.

This study found that Carbon Quantum Dots effectively detected and quantified Co²⁺ ions and methylcobalamin in tap water with high sensitivity and recovery rates between 95% and 105%.

This study investigated dual TCR Treg cells in mouse tissues, revealing a high proportion and diverse pairing patterns compared to single TCR Tregs, providing insights into their origins and characteristics across different tissue locations.

This study found that in noise-exposed FVB/NJ mice and cell models, ivacaftor reduced oxidative stress and hearing damage by maintaining CFTR function and increasing Nrf2 expression, suggesting its potential for treating noise-induced hearing loss.

This study developed the Alopecia Areata Children's Quality of Life Index (AAcQLI) to assess quality of life in children with alopecia areata, demonstrating good reliability and validity in initial tests.