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This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.

This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.

In this case study, PRP and PRF treatments helped achieve complete healing of chronic wounds, including a chemical burn ulcer in three weeks and a pilonidal sinus post-incision in eight weeks, suggesting potential benefits for chronic wound management.

This review discusses the potential benefits of using natural permeation enhancers to improve transdermal drug penetration in formulations like emulgel, a promising topical delivery system for hydrophobic drugs.

This study reports that 71% of patients treated with the gamma-secretase inhibitor PF-03084014 for desmoid tumors experienced dermatologic side effects, such as follicular lesions and pruritic eruptions, which were managed with topical or systemic treatments.

In this study, methylprednisolone pulse therapy was found to be effective for severe alopecia areata patients, especially those with a short disease duration or plurifocal type.

This case report describes a boy with hypothalamic hamartoma experiencing pubertas precox and gelastic seizures, where leuprorelin therapy's effect on pubertas precox was controversial, but valproic acid effectively managed gelastic seizures.

Bullous pemphigoid can look like erythema multiforme, so awareness is needed for proper treatment.

The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.