This review introduces the pilocutaneous syndrome of menopause, a set of skin and hair changes linked to estrogen decline, and discusses its recognition, diagnosis, and management without reporting new clinical results.
May 2025 in “The Journal of Rheumatology” This case report highlights a rare instance of diffuse alveolar hemorrhage in a patient with catastrophic antiphospholipid syndrome, emphasizing the importance of early recognition and multidisciplinary management.
August 2010 in “Oncology Times” This article discusses the approval and perceived potential of Provenge, a new prostate cancer vaccine, highlighting its capability to extend survival in certain patients while also noting ongoing debates about its cost and mechanisms; it reports no new clinical results.
52 citations
,
July 1998 in “Urology” This study found that liarozole is more effective than cyproterone acetate for improving PSA response and survival in metastatic prostate cancer after first-line endocrine therapy, while maintaining quality of life.
January 2015 in “프로그램북(구 초록집)” This case report describes an unusual instance of eruptive syringomas in a 25-year-old man, persisting for about 10 years, which is atypical given the patient's sex and the condition's usual presentation.
This review discusses the pilocutaneous syndrome of menopause, associated with skin and hair changes due to estrogen decline, and highlights an unmet need for recognition and targeted treatment.
88 citations
,
May 2011 in “British Journal of Clinical Pharmacology” This study found that high doses of cyproterone acetate were associated with an increased risk of meningioma, especially with exposure longer than one year.
March 2013 in “The Journal of Urology” This study found that patients with androgenetic alopecia frequently had higher PSA levels and more significant urinary symptoms, likely due to older age, though prostate weight did not differ.
April 2016 in “The Journal of Sexual Medicine” PFS affects some women, steroids easily bought online, hypogonadism info unreliable, low testosterone linked to CVD.
This study reports that prostatitis, affecting many men aged 30 to 50, arises from diverse causes, including bacterial infections and pelvic pain syndromes, and requires treatment strategies specific to its type, such as antibiotics and lifestyle changes.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This case study reports that a 26-year-old woman with epidermolysis bullosa prurogompsa also presented with unique findings of co-existing muscular dystrophy and immune-based myasthenia gravis, with significant improvement following steroid treatment.
10 citations
,
June 2001 in “Annals of neurology” This study reports that patients with Alzheimer's disease have increased levels of polyamines in their hair.
April 2011 in “Cancer Research” In this study, ginsenoside 20(S)-protopanaxadiol-aglycone (PPD) was shown to downregulate androgen receptor expression and inhibit tumor growth in prostate cancer cells.
5 citations
,
June 2021 in “Journal of neurology, neurosurgery and psychiatry” This study found that females exposed to high cumulative doses of cyproterone acetate had a 6–20 fold increased risk of developing meningiomas compared to those on lower doses.
July 1979 in “Archives of Dermatology” This case report describes a 68-year-old woman with benign mucous membrane pemphigoid and unusual keratotic plaques on her extremities, associated with longstanding mouth and eye symptoms and phalangeal swelling.
7 citations
,
January 2013 in “European Urology” This study developed solid lipid nanoparticles for delivering a shRNA-encoding plasmid that effectively reduced 5α-reductase enzyme levels in vitro without significant cytotoxicity, suggesting potential therapeutic applications.
28 citations
,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.
5 citations
,
September 2012 in “The Journal of Urology” This article discusses androgenetic alopecia as a potential early marker for benign prostatic hyperplasia but reports no new clinical findings.
April 2007 in “Nature Clinical Practice Urology” Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
November 2022 in “American Journal of Clinical Pathology” In this case study, concurrent prostatic adenocarcinoma and a rare solitary fibrous tumor were identified on a transurethral resection of the prostate specimen.
5 citations
,
August 2024 in “Drug Discovery Today” This review examines advances in computer-aided drug design for targeting membrane proteins in prostate cancer but reports no new clinical results; it emphasizes the potential of structural insights and compound screening for therapeutic development.
8 citations
,
June 2016 in “Journal of Cutaneous Pathology” This report describes two rare cases of desmoplastic melanoma presenting as alopecia neoplastica, highlighting a potential diagnostic pitfall for clinicians examining patients with scar-like alopecia.
February 2003 in “European Urology Supplements” Baseline PSA levels affect general health and sexual satisfaction in men with BPH treated with finasteride or placebo.
March 2005 in “Current Prostate Reports” August 2025 in “Therapeutics” In this study, low concentrations of DMSO were found to decrease androgen receptor expression and inhibit the migration of prostate cancer cells, suggesting potential as an anticancer therapy.
April 2023 in “Journal of Investigative Dermatology” This study found that MPZL3 plays a crucial role in controlling sebaceous gland size and sebocyte proliferation in mice and humans, implicating its potential involvement in skin disorders like acne and psoriasis.
1 citations
,
April 2012 in “Urology” Self-management can help improve symptoms of benign prostatic hyperplasia.
December 2021 in “Innovation in aging” This study found that frailty independently raises the risk of clinical BPH progression and serious adverse events in older men, suggesting that shared decision-making is essential when considering medical therapy for frail patients.
3 citations
,
January 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study in mice found that topical pumpkin seed oil promoted hair growth and could be a promising alternative treatment for male pattern alopecia.
26 citations
,
June 2003 in “PubMed” In this study, severe hair loss occurred in PKC epsilon transgenic mice treated with DFMO during skin tumor prevention, highlighting a link between polyamine biosynthesis, hair follicle maintenance, and metastasis suppression.