5 citations,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
2 citations,
September 2020 Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.
1 citations,
May 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
September 2012 in “African Journal of Urology” Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
April 2003 in “Experimental Dermatology” The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
417 citations,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy increases bone density in older men with low testosterone levels.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
196 citations,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
130 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
127 citations,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
124 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
92 citations,
November 2003 in “The Journals of Gerontology” Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
75 citations,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
68 citations,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
64 citations,
March 2017 in “Nature communications” Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
54 citations,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
50 citations,
December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
47 citations,
October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
42 citations,
May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
41 citations,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
41 citations,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
40 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
39 citations,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.