research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
Search
for
Sort by
Research
300-330 / 1000+ results 
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Potential Pharmacological Activities of Pumpkin Seeds as a Functional Food: A Comprehensive Review
Pumpkin seeds may improve health due to their rich nutrients and potential to treat various conditions.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Use of Contact Immunotherapy in the Treatment of Skin Diseases Other than Alopecia Areata
Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis
Suppressing very long chain fatty acids is linked to skin cancer.
research Effects of Castration on Benign Prostatic Hyperplasia
Castration significantly reduces prostate size and BPH symptoms.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research JAAD Grand Rounds Quiz on Dermatological Conditions
The document explains the diagnosis and characteristics of woolly hair nevus and alopecia neoplastica.
research Neuronal Mimicry as a Resistance Phenotype in Cancer Cells
Low dose finasteride causes only small changes in PSA levels in older men with BPH.
research Urological Oncology: Testis Cancer and Advances in Oncological Therapy
Finasteride lowers PSA levels in men, certain factors increase testicular cancer risk, and current guidelines for penile cancer may lead to unnecessary surgeries.
research Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop
The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
research Finasteride
Finasteride helps increase or maintain hair in most men but can cause sexual side effects and should not be used by women, especially during pregnancy.
research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research The Rotterdam Study: 2012 Objectives and Design Update
The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research Male Pattern Baldness and Risk of Incident Skin Cancer in a Cohort of Men
Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
research A Risk-Benefit Assessment of Treatment with Finasteride in Benign Prostatic Hyperplasia
Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Docetaxel-Induced Psoriasis: A Case Report
Docetaxel, a chemotherapy drug, was reported to cause psoriasis in a patient for the first time.
research The Efficacy of Dihydrotestosterone Transdermal Gel Before Primary Hypospadias Surgery: A Prospective, Controlled, Randomized Study
Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors
Inactive hair follicle stem cells help prevent skin cancer.
research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer
sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
research Cetuximab-Associated Elongation of the Eyelashes
Cetuximab can cause eyelash growth, which is rare but manageable.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.