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Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Most skin changes during pregnancy go away after giving birth.

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Hair growth slows and shedding increases after childbirth, but most women don't experience excessive hair loss.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Losartan can cause temporary loss of taste.