2 citations
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January 2016 in “SANGYO EISEIGAKU ZASSHI” This study found that nearly all nurses caring for chemotherapy patients showed detectable levels of cyclophosphamide in their urine, indicating significant occupational exposure to this antineoplastic drug.
1 citations
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March 2013 in “Revista de Investigaciones Veterinarias del Perú” This study found that a single application of 0.1% aqueous benzalkonium chloride solution effectively treated dermatomycosis caused by Trichophyton species in guinea pigs.
4 citations
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November 2001 in “Journal of Neuropsychiatry” This case report from the University of Alabama, Birmingham describes a rare paradoxical reaction of increased agitation and hyperactivity in a patient with schizoaffective disorder treated with divalproex sodium.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study concluded that the topical gel VB1953 reduced inflammatory and non-inflammatory acne lesions and resistant bacteria in patients with clindamycin-resistant acne, showing promise as an effective treatment.
48 citations
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February 1999 in “PubMed” This study found that the anticonvulsant effects of progesterone against PTZ-induced seizures in mice require conversion to allopregnanolone, as shown by the reversal of these effects with a 5alpha-reductase inhibitor.
3 citations
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May 1963 in “Radiology” This article reports on five cases of thallium poisoning seen at Hospital Dos de Mayo, Lima, Peru, highlighting the clinical symptoms and diagnostic features observed, including a case confirmed through various laboratory tests.
1 citations
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April 2022 in “The Journal of Urology” This study observed that discontinuation rates due to side effects were similar for penicillamine and tiopronin among cystinuria patients, and switching to the alternative agent was beneficial for half of those experiencing issues.
4 citations
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December 2020 in “Natural Product Sciences” This study identified ten compounds from Eclipta prostrata, with some displaying potent inhibitory effects against α-glucosidase and acetylcholinesterase enzymes.
January 2004 in “Headache” This study found that two-thirds of patients with persistent chronic daily headache showed significant improvement with divalproex sodium treatment, although common side effects included weight gain, tremor, hair loss, and nausea.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” This study examined the vasorelaxant effects of two similar alkaloids, chloroquine and cinchonine, in a model of smooth muscle contractions induced by phenylephrine. Results are not reported in the abstract.
25 citations
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September 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.
In this study, researchers assessed the physical-chemical and microbiological stability of various pharmaceutical ingredients in the vehicle TrichoSolTM, finding differing beyond-use dates for the compounds, such as 180 days for cetirizine hydrochloride, but only 90 days for progesterone at higher concentrations.
1 citations
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September 2016 in “Acta Chromatographica” This study validated a new RP-HPLC method for accurately determining doxazosin mesylate and finasteride in bulk powders and capsule formulations.
3 citations
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March 1981 in “Journal of Toxicology and Environmental Health” This study found that high doses of cloforex and chlorphentermine caused pulmonary lipid histiocytosis and toxic effects in rats, but did not induce pulmonary hypertension.
87 citations
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January 1996 in “Journal of cellular biochemistry” This article discusses ongoing and planned clinical chemoprevention trials for various agents and combinations but reports no new results; it highlights promising new agents and the evolving focus on molecular pathways.
October 2011 in “The American Journal of Gastroenterology” This case report suggests a potential association between esomeprazole use and hepatic injury, highlighting a temporal relationship with liver enzyme elevation that resolved upon discontinuing the drug.
June 2001 in “Annals of Internal Medicine” This commentary discusses challenges in maintaining proper blinding in placebo-controlled trials, illustrated by a study where zinc and placebo lozenges were nearly indistinguishable in taste by participants.
This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.
June 1958 in “Mycopathologia” Selective chemical epilation effectively treats tinea capitis without harmful side effects.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
22 citations
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November 2002 in “Clinical journal of oncology nursing” This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.
22 citations
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March 1932 in “Journal of the American Medical Association” This report describes eleven cases of thallium poisoning in individuals who consumed tortillas made from barley mixed with thallium sulphate, leading to symptoms including tingling, abdominal pain, vomiting, and limb weakness.
1 citations
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January 2014 in “Side effects of drugs annual” This review discusses adverse reactions to antihelminthic drugs and highlights that levamisole, a common street cocaine adulterant, can cause serious side effects, including skin necrosis and vasculitis.
June 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, progesterone showed anticonvulsant effects in mice via a mechanism that is at least partially independent of its metabolism to THP, without significant psychotoxicity.
December 2023 in “Ukraïnsʹkij žurnal sučasnih problem toksikologìï/Ukraïnsʹkij Žurnal Sučasnih Problem Toksikologìï” This study found an increase in criminal and accidental thallium (Tl+) poisonings globally, particularly in Ukraine, partly due to online availability, underscoring the need for better control and diagnosis to prevent severe outcomes and potential misuse during ongoing conflicts.
33 citations
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May 2017 in “Journal of Clinical Oncology” This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.
January 2025 in “International Journal of Scientific Research in Science and Technology” This study validated an HPLC analytical method for evaluating fenasteride in commercial products, finding it to be sensitive, selective, and within acceptance criteria for specificity, precision, and stability, making it suitable for quality control testing.
July 2026 in “Current Issues in Molecular Biology” This study found that Plerixafor, a CXCR4 antagonist, promotes melanogenesis in melanocytes by increasing MITF and tyrosinase expression and enhancing melanocyte migration, and it effectively restores pigmentation in a mouse depigmentation model without toxicity, highlighting its potential for treating pigmentary disorders.
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
31 citations
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October 1992 in “Journal of Clinical Pharmacy and Therapeutics” This study found that while many drugs are reported to cause hair color changes, substantial evidence supporting a true relationship exists mainly for chloroquine and certain cancer chemotherapeutic agents.