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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Certain changes in the SHBG gene may increase the risk of PCOS in Iraqi women.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Early diagnosis and treatment of PCOS can prevent complications and improve symptoms.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

The document is a detailed medical reference on skin and genetic disorders.

Ancient hair can preserve hormones, revealing health and fertility insights.

An 87-year-old woman was diagnosed with type 3 autoimmune polyendocrine syndrome and had multiple autoimmune issues.

The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Skin symptoms can indicate endocrine disorders and have various treatments.

The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

Follicle Stimulating Hormone is important for fertility.

Men with severe hair loss may have poorer sperm quality.

Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Long-term anabolic steroid use can lead to heart and metabolic health issues.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.