June 2025 in “SAS Journal of Medicine” This case study highlights an unusual presentation of folliculitis decalvans by age and sex, emphasizing early diagnosis due to its chronic nature and irreversible consequences.
January 2025 in “The Analyst” In this study, researchers identified a novel biomarker of oxalate metabolism, which plays a crucial role in conditions like hyperoxaluria and kidney stones, marking the first time this detection has been reported.
November 2024 in “Frontiers in Endocrinology” This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.
Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.
January 2019 in “Journal of Entomology and Zoology Studies” This study observed that in Assam Hill Goats, the primary hair follicles had larger diameters and more structural associations compared to secondary follicles, especially in ruminant-age groups.
December 2015 in “Actas Dermo-Sifiliográficas” This review addresses the challenges in treating frontal fibrosing alopecia, highlighting the limited effectiveness of medical treatments and the demand for hair transplantation despite its risks, but it reports no new clinical results.
January 2013 in “Sen'i Gakkaishi” This study found that microfibrils play a crucial role in shaping permanent waves by thioglycolic acid, and treating damaged hair with hydrolyzed keratin improved both waving efficiency and hair damage.
Detailed history and physical examination are crucial for diagnosing hair loss.
37 citations
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May 2018 in “Frontiers in physiology” This study identified key long non-coding RNAs and mRNAs involved in primary wool follicle induction in carpet wool sheep, emphasizing their roles in hair follicle development and skin processes.
April 2025 in “Ukrainian Journal of Veterinary and Agricultural Sciences” This study observed that feeding ewes a water-soluble complex of fatty acids increased primary hair follicle bulb diameter and mitotic activity, suggesting a positive correlation with wool growth.
1 citations
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January 2020 This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
May 2023 in “Jurnal farmasi sains dan praktis” In this research on cinnamon and virgin coconut oil hair tonics, F2 and F3 demonstrated stable physical properties and mild irritation potential, while formula 1 remained non-irritating but less stable regarding pH and viscosity.
May 2009 in “Medical and surgical dermatology/Medical & surgical dermatology” Hair and nail conditions can stabilize or improve over time, and new treatments show promise.
20 citations
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November 1989 in “PubMed” This case report highlights that diagnosing fungal skin infections in immunocompromised patients requires culture for accurate identification, as histologic findings alone can be misleading.
19 citations
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June 2020 in “Animals” This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.
18 citations
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January 1977 in “Annals of Nutrition and Metabolism” This article reviews inherited mineral and trace element disturbances and reports no clinical results; it highlights conditions like hypomagnesaemia and acrodermatitis enteropathica linked to impaired nutrient absorption.
15 citations
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June 2019 in “Biochemical Journal” This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.
10 citations
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January 2013 in “International Journal of Research in Pharmaceutical Sciences” This study found that a microemulsion containing extracts of Hibiscus rosa sinensis and Murraya koenigii was non-irritating and more effective at controlling hair loss than a standard marketed formulation.
9 citations
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March 2015 in “International reviews of immunology” This review discusses the relationship between ectodermal alterations and immunodeficiencies, particularly the roles of hyper-IgE syndrome, ectodermal dysplasia, and FOXN1 gene mutations, but it presents no new research findings.
7 citations
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April 2013 in “Animal Production Science” This study found that manipulating maternal cortisol levels during pregnancy altered Merino sheep wool characteristics, increasing fibre length and reducing crimp frequency in the offspring.
7 citations
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September 1977 in “PubMed” This article describes a new surgical technique called "hair-lifting" for treating male-pattern alopecia, which involves removing sections of bald scalp and repositioning remaining hair.
6 citations
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March 2020 in “Anais Brasileiros de Dermatologia” This report highlights the successful treatment of skin and nail manifestations in a patient with primary hypothyroidism using levothyroxine, emphasizing the role of cutaneous symptoms in identifying thyroid disease.
6 citations
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January 2013 in “Urology” This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
5 citations
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January 2016 in “Genetics and Molecular Research” This study identified 617 differentially expressed genes in cashmere goat hair follicles, which are involved in key biological processes and provide insights into hair follicle development.
5 citations
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October 2011 in “Small ruminant research” This study found that seasonal changes significantly affected hair follicle activity and fibre growth in Merghoz goats, with variations seen in feed intake and growth patterns across different seasons.
4 citations
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January 2014 in “Dermatology” This case report details a woman with autoimmune primary ovarian insufficiency linked to hormonal contraception discontinuation, who achieved pregnancy through ovarian stimulation and in vitro fertilization despite typically low fertility in such conditions.
2 citations
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May 2025 in “Aesthetic Surgery Journal” This review highlights that hair transplantation can be a reconstructive treatment for various types of alopecia, including secondary scarring, congenital, and select primary scarring and nonscarring dermatological alopecias.
2 citations
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January 2012 in “Zhongguo nongye Kexue” In this study, epidermal growth factor expression significantly correlated with the development of secondary hair follicles in Jining Gray goats until two months of age.
1 citations
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September 2025 in “PLoS ONE” This study found that disrupted cholesterol homeostasis in scalp samples from cicatricial alopecia patients hinders hair regrowth by affecting hair follicle stem cell markers, with resulting effects confirmed in vitro and in animal models.