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Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

AMT may cause hair loss and changing dWAT activity could help treat it.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.

Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Minoxidil works in liver and outer hair root sheath for hair growth.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.

Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.

Three dogs with a rare skin condition improved with treatment.

PCOS is common in young women, especially those aged 21-30, and often involves symptoms like irregular periods, weight gain, and acne.

A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.

The document concludes that proper diagnosis and treatment of follicular disorders are crucial, with specific treatments for conditions like acne, drug-induced eruptions, and rosacea.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.