March 2002 in “Reactions Weekly” Some birth control pills increase blood clot risk; use them for specific conditions only.
March 2024 in “BMC women's health” This study found that free testosterone levels were 29% higher with the levonorgestrel implant than with the DMPA injection, which may impact sexual function, mood, and side effects like acne.
21 citations
,
April 2010 in “Molecular Medicine Reports” This review discusses zinc supplementation as a complementary therapy for chronic hepatitis C, noting its potential benefits in improving treatment outcomes and reducing side effects, but reports no new clinical results.
26 citations
,
October 2011 in “Biological trace element research” This study observed that lower serum copper levels may be linked to premature hair graying in young patients compared to controls.
2 citations
,
November 2004 in “Hospital pharmacy” This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.
7 citations
,
December 2017 in “Basrah Journal of veterinary Research” This study in Basra province sheep reported that zinc and copper deficiencies were linked to various clinical signs and affected oxidative stress and antioxidant levels.
November 2023 in “Biology” This study investigated 130 patients and found a significant inverse correlation between copper content and the copper/zinc ratio in hair samples and the extent of coronary artery disease, while zinc content alone showed no significant relationship with disease extent.
6 citations
,
September 2002 in “Acta pædiatrica” This case study observed that long-term itraconazole and budesonide use in a cystic fibrosis patient led to iatrogenic Cushing's syndrome due to inhibited metabolic clearance of budesonide, suggesting a need for regular adrenal insufficiency monitoring in such treatments.
37 citations
,
September 2002 in “Acta pædiatrica” In this study, a patient with cystic fibrosis developed iatrogenic Cushing's syndrome due to impaired clearance of budesonide from concurrent itraconazole use, highlighting the need for regular monitoring in such combination therapies.
June 2018 in “Korean Journal of Family Practice”
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.
2 citations
,
April 2025 in “Biomedicine & Pharmacotherapy” This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.
8 citations
,
April 1990 in “Hormone and Metabolic Research” This study found that a combination of cyproterone acetate and ethinyl estradiol over one year did not affect glucose tolerance but increased total cholesterol, HDL cholesterol, and triglycerides in patients with moderate hyperandrogenism.
December 1951 in “Journal of the American Medical Association” This article reports a case of hair loss and pigmentation changes in a man after using propylthiouracil alongside iodine solution for thyroid and diabetic conditions, providing clinical observations without broader conclusions.
6 citations
,
September 1957 in “Poultry Science” This study found that adding molybdenum to poultry diets depressed growth without affecting feather pigmentation, and copper supplementation tended to counteract the growth inhibition.
27 citations
,
March 2012 in “Dermatologic Therapy” In this study, all five patients with zinc deficiency-related hair loss experienced improvement or recovery of their condition after receiving oral zinc treatment.
May 2014 in “The Journal of Alternative and Complementary Medicine” Higher levels of chromium, selenium, and copper in hair are linked to increased insulin resistance in visceral-obese adults.
1 citations
,
October 2011 in “Hospital Pharmacy” This article highlights the importance of recognizing, preventing, and reporting adverse drug reactions to the FDA's MedWatch program, but does not present new research findings.
May 2026 in “Pharmaceuticals” This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
17 citations
,
January 1981 in “International Journal of Food Sciences and Nutrition” This article reviews the roles of zinc and copper in biological processes, especially their implications for metabolism and deficiency-related disorders, but it does not present new clinical results.
12 citations
,
June 2024 in “JAAD Case Reports” Tirzepatide may improve hair loss by reducing insulin resistance.
12 citations
,
September 1981 in “Acta Dermato Venereologica” This case study reports that oral zinc therapy improved hair growth and pigmentation in a young girl with sucrase deficiency and low zinc levels.
15 citations
,
February 2019 in “Journal of clinical medicine” In this animal study, atorvastatin co-administered with trastuzumab reversed trastuzumab-induced cognitive impairment (chemo-brain) and improved its anti-cancer efficacy without causing hair loss.
December 2025 in “npj Breast Cancer” In the phase 3 CAPItello-291 trial, capivasertib combined with fulvestrant significantly increased progression-free survival in patients with advanced breast cancer with specific genetic alterations, but the authors highlight that managing side effects like diarrhea, rash, and hyperglycemia is crucial for optimizing treatment adherence and outcomes.
January 2018 in “Journal of Crohn s and Colitis” This study found that high-dose intravenous ferric carboxymaltose may reduce inflammatory activity in patients with inflammatory bowel disease and iron deficiency anaemia, as evidenced by decreased CRP levels and improved clinical disease indices.
April 2026 in “Al-Kufa University Journal for Biology” This pilot study observed that post-bariatric surgery, both zinc and iron deficiencies increased among Iraqi patients, underscoring the importance of lifelong nutritional monitoring and targeted supplementation to address these issues and prevent related complications.
5 citations
,
January 2023 in “IDCases” In this case report, a 45-year-old man developed acute fatal pancytopenia and other severe adverse reactions 10 days after starting albendazole and praziquantel for pulmonary cystic echinococcosis.
20 citations
,
July 1990 in “Clinical and experimental dermatology” In this study, women treated for androgen-dependent alopecia with CPA EE2 therapy experienced significant decreases in serum vitamin B12, hemoglobin, and hematocrit levels after six months.
23 citations
,
August 1975 in “Experimental Biology and Medicine” This study found that supplementing pregnant and lactating mice with high dietary copper improved survival and physical traits in mice carrying the crinkled mutation, suggesting copper's role in modulating gene expression.