29 citations
,
December 1998 in “Seminars in Cutaneous Medicine and Surgery” This review examines recent approvals and emerging treatments for androgenetic alopecia, discussing newly approved drugs like Propecia and Rogaine Extra Strength 5%, but without presenting new clinical results.
30 citations
,
January 2000 in “Dermatologic Clinics” This article reviews the genetic and psychological aspects of androgenetic alopecia in men and women, reporting no new clinical findings while emphasizing the broad impact of this hair loss condition.
22 citations
,
March 2000 in “Clinics in Dermatology” This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.
6 citations
,
May 2011 in “Pharmacognosy Journal” This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
10 citations
,
January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
June 2023 in “Research Square (Research Square)” This study demonstrated that dietary cupric citrate improved growth performance and nutrient utilization in broilers, while also altering their intestinal microbiota and increasing the pH in the duodenum and jejunum.
74 citations
,
July 1995 in “PubMed” This study suggests that reversible hypopigmentation in homocystinuric patients may result from tyrosinase inhibition by homocyst(e)ine, with in-vitro experiments showing copper sulfate reversing this inhibition.
25 citations
,
June 1998 in “Biological Trace Element Research” This study found that young healthy women with a family history of noninsulin-dependent diabetes mellitus exhibited higher zinc and lower copper concentrations in hair compared to those without such a family history, suggesting a possible Cu-Zn antagonism.
July 1998 in “Hair transplant forum international” This article discusses the need to focus on improving telogen effluvium and healing speed in hair transplantation but reports no new research findings.
In this study, a copper-deficient diet in rats led to a significant decrease in blood and liver copper levels without causing clinical symptoms, while hair leachable copper and bone copper remained unchanged.
August 2025 in “Journal of the American Academy of Dermatology” 12 citations
,
June 2022 in “International Journal of Molecular Sciences” In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.
April 2019 in “Journal of the Endocrine Society” This case report suggests that a supplement containing biotin, beta carotene, vitamin C, zinc, and copper may improve insulin resistance markers and hair loss in a patient with non-classic 11-hydroxylase deficiency.
1 citations
,
April 2022 in “The Journal of Urology” This study observed that discontinuation rates due to side effects were similar for penicillamine and tiopronin among cystinuria patients, and switching to the alternative agent was beneficial for half of those experiencing issues.
July 2023 in “Journal of Clinical Medicine” This study reviews current treatments for PCOS and evaluates Tirzepatide as a potential option for its management, suggesting possible benefits for those with obesity and metabolic syndrome but not for those of normal weight.
2 citations
,
January 1977 in “PubMed”
12 citations
,
July 1979 in “International Journal of Dermatology” This article reviews the clinical manifestations and contributing factors of acute zinc depletion syndrome, reporting no new results but discussing prevention and treatment strategies.
2 citations
,
March 2013 in “BMJ Case Reports” In this case study, zinc deficiency persisted despite supplementation in a patient with severe malnutrition and empyema, potentially due to nutrient absorption competition and proton pump inhibitor use.
16 citations
,
March 1986 in “Biochemical Pharmacology” 246 citations
,
April 1976 in “Annals of Surgery” In this study, a syndrome of zinc deficiency was observed in adults receiving intravenous feeding, with zinc supplementation improving symptoms except for delayed hair regrowth.
June 2011 in “Journal of clinical and experimental investigations” This study suggests that oral zinc sulphate may be an effective and safe treatment for thallium poisoning, particularly in improving dermatological symptoms and reducing the progression of the condition.
40 citations
,
July 1981 in “Journal of Neuropathology & Experimental Neurology” In this study, brindled mutant mice with clinical features similar to kinky hair syndrome showed marked improvement and prevention of neuronal degeneration after receiving cupric chloride injections, with timing of administration being crucial.
114 citations
,
October 2009 in “Gastroenterology” This review discusses zinc's role as an essential trace element in human nutrition, particularly its importance in total parenteral nutrition, and reports no new clinical results.
November 2007 in “Hospital pharmacy” This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.
2 citations
,
June 2011 in “Journal of clinical and experimental investigations” This study found that oral zinc sulphate appeared effective and safe for treating thallium poisoning, particularly in reducing hair and skin symptoms and mitigating its severe progression in patients.
102 citations
,
October 2010 in “Molecular Pharmaceutics” In this study, copper-doxorubicin liposomes with multidose therapy reduced systemic toxicity compared to ammonium sulfate-loaded doxorubicin liposomes, while combinatorial strategies further enhanced tumor regression and accumulation.
16 citations
,
June 1983 in “Journal of Neurochemistry” This study found that copper injections increased dopamine-β-hydroxylase activity in the brains of mottled mice, an animal model for Menkes' syndrome.
2 citations
,
June 1986 in “Journal of Clinical Pharmacy and Therapeutics” This study demonstrated that certain metal salts can bind to sodium valproate and discussed the potential link to hair loss in patients treated for epilepsy.