TLDR Copper therapy improved health and enzyme activity in mice with copper deficiency.
The study investigated the effects of copper therapy on the mottled (Mo) mouse, an animal model for Menkes' kinky hair syndrome, a congenital copper deficiency disorder. Researchers administered intraperitoneal copper chloride injections (10 μg/g) on postnatal days 7 and 10, which resulted in clinical and morphological improvements. Additionally, these copper injections increased the activity of dopamine-β-hydroxylase, a copper-dependent enzyme, in the brains of the Mo mice, suggesting potential therapeutic benefits for addressing neurochemical changes associated with the disorder.
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