Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that dermal adipocytes play a significant role in skin aging, particularly through the process of adipocyte-myofibroblast transition, highlighting them as potential targets to combat aging in chronically photo-damaged skin.

This study found that alopecia areata was associated with increased serum levels of retinol-binding protein-4 compared to controls, but no correlation with disease severity was observed.

The researchers reported that different allergens showed unique patterns based on season, gender, and age among patients with allergic skin rashes, with notable differences in allergen predispositions across groups.

This study found that allopregnanolone has a bimodal effect on prolactin secretion in sheep, stimulating PRL mRNA expression but inhibiting hormone release under stress and pregnancy conditions.

This study found that specific genes related to vascular endothelial growth factors are critical for feather maturity in certain chicken breeds, identifying key genetic markers that could enhance breeding efficiency.

This study conducted in fertility clinics in Abbottabad found that hyperprolactinemia is the most prevalent cause of secondary amenorrhea, affecting 31.7% of cases, followed by drug-induced amenorrhea in 14.3% of patients, with oral contraceptives and omeprazole as common factors.

This review discusses the reproductive challenges and potential pathophysiological mechanisms related to anorexia nervosa, noting possible long-term effects on fertility and pregnancy outcomes.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

This study found that the global prevalence of alopecia areata is estimated at 1.93%, affecting around 15.05 million people, with significant regional and demographic variations.

The researchers found that combining permethrin (44%) and fluralaner effectively reduced tick load in moose calves, as indicated by less severe hair loss, compared to untreated calves, while topical permethrin (5%) alone had no clear effect on tick load, body mass, or hematocrit.

This study found that premenopausal exercising women with oligomenorrhea had lower triiodothyronine levels and truncal fat percentage compared to other groups, suggesting distinct energetic and reproductive profiles.

This source presents an expert consensus framework for determining which Australian patients with alopecia areata should receive subsidized JAK inhibitor therapy, emphasizing the need for future research including patient perspectives to enhance criteria, ensure fair treatment access, and evaluate real-world outcomes.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.

This study found that mange-infected bare-nosed wombats have increased heat loss, higher metabolic rates, altered behavior, and disrupted fatty acid composition compared to healthy individuals.

This paper reviews existing and emerging therapies for alopecia areata, describing the impact of targeted treatments in this field, and introduces a global network of disease registers to study the long-term safety and effectiveness of these new options.

In this study, the isotopic fractionation between tissues and diets of captive Japanese macaques was quantified, particularly noting hair's response to diet changes in controlled conditions, but these findings underscore the complexity of reconstructing long-term dietary history.

This study found that adult and adolescent patients with alopecia areata in the US and Europe are willing to accept significant risks of serious side effects, such as infection and cancer, to achieve effective hair regrowth with Janus kinase inhibitors.

This study found that among a diverse sample of US adults, individuals with skin of color had a higher prevalence of alopecia areata compared to Whites.

This study found that rhesus macaques with inhibited or anxious temperaments had less alopecia, suggesting temperament may influence hair loss in these animals.

This study found that platelet rich plasma was effective in treating alopecia areata, with 65% of patients responding well to treatment.

This study found that long-term use of difluprednate ophthalmic emulsion in dogs can lead to HPA axis suppression and potentially cause iatrogenic hyperadrenocorticism, with localized alopecia suspected due to dermal absorption.

This review discusses the prevalence, diagnosis, treatment, and prevention of zoophilic dermatophyte infections in small exotic mammals and reports no new clinical findings; it emphasizes the need for veterinary guidance and public awareness.

This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.

In this study, researchers found that a single oral dose of afoxolaner was safe and effective in treating a severe case of Trixacarus caviae mange in a guinea pig, achieving full remission of clinical signs and mite eradication within 4 weeks without needing repeated treatment.

In these aquatic laboratory studies, researchers found that Finasteride reduced dihydrotestosterone levels in fathead minnows and increased gene expression related to androgen pathways in both minnows and medaka, indicating potential conservation of pharmaceutical effects on androgen biosynthesis across different species.

In this study, feeding H-line chickens a diet with 1.0% tyrosine for 40 days significantly increased melanin deposition in feathers and revealed changes in gene expression related to melanin pathways, suggesting tyrosine's involvement in regulating feather color through the EDNRB2 regulatory network.