Prevalence and Hormonal Profiling of Secondary Amenorrheic Patients Presenting to a Fertility Clinic – An Observational Study
October 2025
in “
Česká gynekologie
”
Studysummary This study conducted in fertility clinics in Abbottabad found that hyperprolactinemia is the most prevalent cause of secondary amenorrhea, affecting 31.7% of cases, followed by drug-induced amenorrhea in 14.3% of patients, with oral contraceptives and omeprazole as common factors.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study conducted on 126 patients with secondary amenorrhea in Abbottabad fertility clinics found that hyperprolactinemia is the most common cause, affecting 31.7% of patients, followed by drug-induced amenorrhea at 14.3%. Among those with drug-induced amenorrhea, 38.9% used oral contraceptives, 27.8% used omeprazole, and 33.3% used other drugs. Common symptoms included headache (79.4%), fatigue (78.6%), and hair loss (65.9%). The findings highlight the importance of considering hyperprolactinemia and drug use in the clinical management of secondary amenorrhea.
