Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
9 citations,
February 2018 in “The Journal of Dermatology” A new mutation in the LIPH gene was found to cause a rare hair disorder in a Japanese boy.
April 2015 in “Dentistry 3000” Premature hair graying in the face may be influenced by genetics and environment.
22 citations,
January 2013 in “International Journal of Trichology” Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.
A 32-year-old man with early graying hair shows a unique pattern, suggesting more research is needed on why hair grays early.
January 2013 in “International Journal of Trichology” A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.
April 2024 in “BMB Reports” Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
30 citations,
November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
4 citations,
July 2019 in “IOP conference series” Most young men with early gray hair have low vitamin D but normal iron levels.
16 citations,
January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Low levels of vitamin B12 and ferritin are linked to early hair graying.
303 citations,
August 1971 in “The American Journal of Medicine” Melanocytes are destroyed by factors needed for melanin production, causing vitiligo and gray hair.
17 citations,
November 2010 in “Perspectives on Psychological Science” Feeling younger can improve health and extend life.
20 citations,
July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
5 citations,
March 2015 in “Clinical and Experimental Dermatology” Chemotherapy caused a woman's permanent hair loss and early menopause.
7 citations,
July 2020 in “Dermatologic therapy” Premature graying of hair is linked to various health issues and can sometimes be reversed by treating underlying conditions.
1 citations,
November 2022 in “International journal of trichology” A woman's premature gray hair turned mostly black again after using Greyverse solution and hair supplements for 5 months.
May 2024 in “Rossijskaâ oftalʹmologiâ onlajn” Early treatment with corticosteroids improved her eye condition significantly.
56 citations,
August 2019 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that Telogen Effluvium is a hair loss disorder that can be assessed with the modified wash test and may be treated with clobetasol foam, with patient management being important.
53 citations,
January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
13 citations,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
2 citations,
May 2017 in “Maturitas” Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
September 2022 in “International Journal of Health Sciences (IJHS)” Low zinc levels may contribute to hair loss due to increased oxidative DNA damage.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
12 citations,
December 2005 in “PubMed” Some men with early hair loss may have similar hormonal changes to women with Polycystic ovary syndrome, and could be at risk for developing type 2 diabetes.
7 citations,
December 2018 in “Journal of Cosmetic Dermatology” Eating vegetarian, having allergies, and family history might be linked to getting gray hair early.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
2 citations,
January 2023 in “Sexual Medicine” The Men's Training Cup Keep Training masturbation aid may help delay ejaculation and improve erectile function.
April 2024 in “Nepal journal of dermatology, venereology & leprology” Premature graying of hair is common and stressful, but not well understood or treated.