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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Finasteride improves hidradenitis suppurativa in children with no adverse effects.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Using tiny fat particles to deliver arginine to hair follicles could be a new way to treat hair loss.

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Laser hair removal is effective for dark hair but needs improvement for nonpigmented or fine hairs.

Antiandrogen therapy helps treat genetic hair loss.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

Low-level laser therapy improves hair growth and dermal papilla cell function.

Testosterone helps human pancreatic cells increase insulin release.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

PRP treatment may promote hair growth and improve hair density in women with AGA, but more research is needed.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.