research Co-Editors' Messages
This issue features tributes to Dr. O'Tar Norwood, commemorating his legacy in the hair restoration community, and reports no new results.
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450-480 / 1000+ results research 土-P4-517 がん化学療法レジメン管理における薬剤師の関与に対する検討(がん薬物療法(レジメン管理と運用),ポスター発表,一般演題,再興、再考、創ろう最高の医療の未来)
This study found that hair contains tightly bound lipids such as cholesterol sulfate, cholesterol, fatty alcohols, and free fatty acids, which are resistant to solvent extraction.
research Attenzione divisa nei pazienti con cerebrolesione acquisita
This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.
research PD35-08 ASSOCIATION OF COMMON MEDICATION WITH PROSTATE-SPECIFIC ANTIGEN LEVEL IN 45-YEAR-OLD GERMAN MEN: RESULTS OF THE PROBASE TRIAL
This study found that in 45-year-old German men, the use of metformin, insulin, and ACE inhibitors was associated with lower PSA levels, while low dose finasteride resulted in notable PSA decrease.
research Platelet-Rich Plasma Hybridized Adipose Transplant (PHAT) for the Treatment of Hair Loss
research PD16-01 NEW INSIGHT OF PSA REDUCTION DURING FINASTERIDE THERAPY
This study observed that finasteride therapy reduced PSA levels by about 40% over a year in Chinese patients with benign prostatic hyperplasia, with varying effects based on baseline PSA levels.
research America - A Diversity of Life Styles.
This Phase II study found that BAY 43-9006, given at 400 mg orally twice daily, led to stable disease in 30% and tumor reduction in 40% of renal cell carcinoma patients.
research 778 Designing and utilizing a c-Rel specific bioassay in drug repurposing screen for HNSCC
A new test helps find drugs to treat head and neck cancer by targeting c-Rel.
research Homologous recombination induced by doxazosin mesylate and saw palmetto in the Drosophila wing‐spot test
This study found that finasteride was nongenotoxic in Drosophila, while doxazosin mesylate and saw palmetto induced homologous recombination, indicating potential genotoxic actions under the test conditions.
research 083 The effect of topical hair growth promoters on internal calcium of human outer root sheath cells(ORSCs)
research Enhancing Solubility and Dissolution Behavior of Finasteride Using Solid Dispersion Technique by Carrier Screening and the New Preparation Instrument
research Abstract PS1-01-19: Exploratory Study on the Efficacy and Safety of Combined Scalp Cooling and HairRepro MEDIα for Chemotherapy-Induced Alopecia in Japanese Breast Cancer Patients
This study found that combining the PAXMAN scalp cooling system with HairRepro MEDI α lotion led to a 50% success rate in reducing chemotherapy-induced alopecia and achieved complete hair regrowth by 3 months in Japanese breast cancer patients, suggesting enhanced efficacy over scalp cooling alone.
research A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets
Quickly get finasteride from tablets using easy methods.
research 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia
This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
research Finasteride, pharmacogenomics, and suicide risk: a public health concern
research Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5α-reductase II
SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
research Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender
In this study, researchers found that a composition containing mannose-6-phosphate significantly reduced the total skin pore area by 24% in women after 56 days and by 30.2% in men after 7 days, suggesting its effectiveness in improving pore appearance by targeting dermal and epidermal modifications.
research In vivo and in silico evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats
This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
research Allelic frequencies for the seventeen Y-STR loci observed in Iraqi male patients with prostate cancer
This study found that certain Y-chromosome alleles may influence susceptibility to prostate cancer among Iraqi males, suggesting potential genetic screening markers for the disease.
research Human Recombinant Hyaluronidase as an Adjunct in Donor Strip Harvesting
This article discusses the introduction of human recombinant hyaluronidase in hair restoration surgery and presents no new clinical results.
research rwSALT: a regrowth-weighted SALT score providing direct pixel-level measurement rather than visual estimation
This tool was developed to enhance reproducibility and sensitivity in measuring partial hair regrowth in alopecia areata patients, particularly those undergoing JAK inhibitor therapy, using scalp photographs.
research PRP for androgenetic alopecia
research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models
This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.
research In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
This study found that the metabolism of finasteride in rat hepatic microsomes involves key hydroxylation steps, highlighting the role of a novel enzyme in 6 alpha-hydroxylation.
research The effect of 1540?nm fractional erbium?glass laser in the treatment of androgenic alopecia
The 1540nm fractional erbium-glass laser helps treat hair loss caused by hormones.
research MP27-18 STATEWIDE GEOGRAPHIC PRICE VARIATION OF GENERIC BPH MEDICATIONS
This study found that big chain pharmacies in Pennsylvania charged significantly higher prices for generic BPH medications compared to independent pharmacies, which had more regional price variation.
research Thrombotic risk minimization for Diane‐35 and generics
This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.
research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor
This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
research MP73-14 TRANSURETHRAL RESECTION URINARY RETENTION PREDICTOR (TURP) SCORE: A NOVEL PERIOPERATIVE PREDICTOR OF POST-OPERATIVE URINARY RETENTION
This study identified several patient-specific factors that can predict both the likelihood of undergoing and failing a post-TURP void trial, aiding in the selection of candidates for immediate assessment.
research Abstract ED05-04: Presurgical models to effectively screen preventive agents
This study provides evidence supporting the feasibility of presurgical, window-of-opportunity models to evaluate the preventive potential of candidate agents in cancer, using cases from breast, prostate, and colorectal settings.