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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Use minoxidil for hair loss treatment; assess results after 6 months.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Some women with common hair loss may develop permanent hair loss.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.