research The Efficacy and Use of Finasteride in Women: A Systematic Review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
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research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research The Metabolic Syndrome-Associated Small G Protein ARL15 Plays a Role in Adipocyte Differentiation and Adiponectin Secretion
ARL15 is important for fat cell development and the release of the hormone adiponectin.
research Male Hormonal Contraception: Looking Back and Moving Forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Dysplastic Nevi, Cutaneous Melanoma, and Other Skin Neoplasms in Patients with Myotonic Dystrophy Type 1: A Cross-Sectional Study
People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.
research Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia
Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
research Effectiveness of Finasteride on Patients with Male Pattern Baldness Who Have Different Androgen Receptor Gene Polymorphism
Finasteride works better for baldness in people with shorter gene repeats.
research Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles
Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Atypical Cushing's Syndrome in Dogs: Arguments For and Against
The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Copy Number Variation Regions in Nellore Cattle: Evidence of Environmental Adaptation
Nellore cattle have genetic variations linked to their adaptation to tropical environments.
research The Combination of Overweight and Smoking Increases the Severity of Androgenetic Alopecia
Overweight smokers have worse hair loss.
research Overexpression of IL-18 in the Proliferative Phase Endometrium of Patients With Polycystic Ovary Syndrome
Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.
research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men
Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
research Disease Versus Disease: How One Disease May Ameliorate Another
Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
research Developmental Genetics of Color Pattern Establishment in Cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Cognitive and Mood Side Effects of Lower Urinary Tract Medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research Androgenetic Alopecia: Drug Safety and Therapeutic Strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Male Pattern Baldness and Risk of Incident Skin Cancer in a Cohort of Men
Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
research Assessment of Vitamin D Receptors in Alopecia Areata and Androgenetic Alopecia
Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.
research Expression of Bioactive Recombinant Human Fibroblast Growth Factor 10 in Carthamus Tinctorius L. Seeds
Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.
research Study of Seed Hair Growth in Populus Tomentosa, an Important Character of Female Floral Bud Development
Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.
research Prevalence of Cervical Insufficiency in Polycystic Ovarian Syndrome
Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
research Cutaneous Manifestations of Metabolic Diseases: Uncommon Presentations
Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.