1 citations
,
January 2004 in “Elsevier eBooks” This review discusses the complexities and challenges in treating polycystic ovarian syndrome and concludes that while lifestyle and insulin-sensitizing treatments show promise, randomized controlled trials are lacking.
951 citations
,
December 2013 in “Clinical epidemiology” This article reviews the prevalence, risk factors, and clinical manifestations of polycystic ovary syndrome, highlighting current treatment and management options, but reports no new research findings.
18 citations
,
June 1999 in “Statistical Methods in Medical Research” This paper reviews the role of pharmacokinetic/pharmacodynamic modeling in drug development, emphasizing its application for drug dosing guidance, safety resolution, and therapeutic monitoring improvement, without presenting new clinical results.
September 2023 in “Research Square (Research Square)” This study describes the development of a prototype clinical expert system that uses a belief rule-based inference methodology to improve the risk stratification and diagnosis of polycystic ovary syndrome by addressing uncertainties in clinical data and domain knowledge.
August 2022 in “Journal of Education Health and Sport” This article discusses the prevalence and impact of polycystic ovary syndrome on reproductive-aged women and reports no new clinical findings.
3 citations
,
April 2019 in “Journal of psychosexual health” This review discusses the psychiatric and sexual comorbidities of PCOS, emphasizing the need for a multidisciplinary approach to manage sexual dysfunction due to high prevalence rates found in recent studies.
5 citations
,
April 2013 in “Current Problems in Pediatric and Adolescent Health Care” This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.
21 citations
,
January 2003 in “Seminars in reproductive medicine” This review outlines the underlying pathophysiology and treatment options for the androgen excess and reproductive and metabolic manifestations of polycystic ovary syndrome, but reports no clinical results.
July 2026 in “International Journal of Innovative Technologies in Social Science” This review found that while treating keratosis pilaris is challenging, current therapies can lead to significant improvement, particularly when tailored to the individual's specific disease phenotype and concerns.
February 2012 in “InTech eBooks” This review discusses the impact of polycystic ovary syndrome on cardiovascular risk and reports no new clinical findings.
44 citations
,
November 2011 in “The Journal of Dermatology” This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.
815 citations
,
April 2010 in “The Journal of Clinical Endocrinology & Metabolism” This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.
138 citations
,
August 2020 in “Frontiers in Endocrinology” This review discusses expert consensus on PCOS, emphasizing its impacts and supporting evidence-based treatments, while recommending further research into nutraceutical benefits for managing the condition; it reports no new clinical results.
December 2025 in “International Journal of Research in Dermatology” This study observed that keratosis pilaris is the most prevalent follicular keratotic disease, especially in adolescent and young adult females, and emphasized the key role of dermoscopy and histopathology in distinguishing it from other similar disorders and aiding in diagnosis.
41 citations
,
June 2007 in “British Journal of Dermatology” This study found that men with Kennedy disease have a significantly lower risk of androgenetic alopecia, likely due to androgen receptor gene alterations from the disease's polyglutamine expansion.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a 26-year-old woman with polycystic ovarian disease and advanced hair loss (Ludwig Grade III) showed reduced hair shedding and improved hair density after four sessions of platelet-rich plasma combined with microneedling, with no reported adverse effects.
March 2023 in “Scholars international journal of obstetrics and gynecology” This article reviews the metabolic and endocrine complexities of PCOS, emphasizing the importance of lifestyle changes and medical management in addressing its various symptoms and complications, but reports no new clinical results.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that 6.1% of new patients seeking PRP therapy for hair loss had undiagnosed cicatricial alopecia, highlighting the importance of proper diagnosis by trained dermatologists to optimize treatment outcomes.
26 citations
,
June 2003 in “PubMed” In this study, severe hair loss occurred in PKC epsilon transgenic mice treated with DFMO during skin tumor prevention, highlighting a link between polyamine biosynthesis, hair follicle maintenance, and metastasis suppression.
1 citations
,
April 2008 in “Progrès en Urologie” Systematic end-of-trial biopsies are the most reliable way to assess outcomes.
November 2017 in “Elsevier eBooks” This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.
In this study, researchers found that NKB placental mRNA expression was higher in women with PCOS, particularly in pregnancies with female offspring, and that NKB expression varied with fetal gender, suggesting a role in PCOS-related placental dysfunction.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
11 citations
,
January 1997 in “Skin Pharmacology and Physiology” This study found that bisindolylmaleimide PKC inhibitors increased DNA synthesis in mouse hair follicles, suggesting that PKC may inhibit hair follicle proliferation.
May 2024 in “IP Journal of Nutrition Metabolism and Health Science” This study found that an educational program significantly improved knowledge about polycystic ovary syndrome and its prevention among adolescent girls at a selected college.
May 2026 in “International Journal of Current Pharmaceutical Review and Research” This article discusses the causes of polycystic ovary syndrome, including environmental pollutants, genetics, and oxidative stress, and explains how these factors contribute to symptoms like irregular menstrual cycles and obesity without reporting new clinical results.
May 2024 in “International Seven Multidisciplinary Journal” This study reviewed the literature to explore the dermatological symptoms associated with Polycystic Ovary Syndrome, such as hirsutism and acne, highlighting the importance of a multidisciplinary approach for optimal management of the syndrome, including controlling circulating androgen levels.
11 citations
,
September 2024 in “Journal of Advanced Research” This study found that PC 3DP models are reliable preclinical tools that could potentially customize treatment strategies and predict patient prognoses by correlating drug sensitivity profiles with clinical outcomes, though larger patient cohort validation is needed to confirm clinical utility.
4 citations
,
July 2019 in “Children (Basel)” This review discusses recent findings on pathogenic mechanisms, diagnostic criteria, and treatment options for PCOS but reports no new clinical results.
15 citations
,
January 2019 in “Gynecological Endocrinology” This article discusses the need for a globally standardized protocol for epidemiologic studies of polycystic ovary syndrome to improve study comparability and public health policy.