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Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Spironolactone plus finasteride reduces hirsutism more effectively.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Blocking a specific protein signal can make hair grow on mouse nipples.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.

Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

Women with scarring alopecia have a lower quality of life and more anxiety and depression than those with non-scarring alopecia.

Skin cells can help create early hair-like structures in lab cultures.

Chronic exposure to sunlight may worsen male pattern baldness and protecting the scalp from the sun could slow it down.

The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.