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This study found that C. japonicum flower extract significantly increased melanin content and cellular activity in human melanocytes and may improve follicular depigmentation and vitiligo through cAMP signaling.

This study found that Sox2 within dermal papilla cells in the hair follicle regulates hair pigmentation, influencing the type and production of melanin.

This review examines the evolution of human skin pigmentation and its genetic basis, suggesting that variations might be due to a few interacting gene pairs, and reports no new research findings.

Harris et al. describe a new mouse model for vitiligo, where interfollicular melanocytes are retained and melanocyte-targeting immune responses are simulated, aiding the development of immunomodulatory therapies.

In this study, researchers found that skin pigmentation alterations in a mouse model of Carney complex may be caused by specific dermal fibroblasts promoting melanogenic signaling.

This article discusses localized repigmentation of hair, suggesting it may be an indicator of underlying melanoma, and emphasizes the need for careful diagnostic evaluation.

This study found that 5 alpha-dihydrotestosterone increased pigmentation in dorsal spots and scrotal skin of prepubertal male Syrian hamsters, while estradiol decreased scrotal skin melanocytes and reversed androgen-induced pigmentation in costovertebral spots.

This study observed that white hair follicles in vitiligo patients may repigment following epithelial grafting and phototherapy, suggesting potential cosmetic improvements in vitiligo treatment.

This case report documents an unusual instance of follicular vitiligo in a young woman, characterized by selective hair depigmentation on the forearms, distinctive dermoscopic and Wood's lamp findings, and histological evidence suggesting functional impairment rather than complete loss of follicular melanocytes.

This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.

The researchers reported that Gambogic Amide may prevent hair greying and promote hair growth by maintaining follicle pigmentation in vitro through activation and migration of melanocytes.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.

In this study, rapamycin was found to increase hair follicle pigmentation and prolong anagen duration in cultured human scalp hair follicles, suggesting it could be explored as an anti-greying agent.

This study found that the cytoplasmic dynein component Dynlt3 is essential for effective melanosome transport and transfer in mouse melanocytes, linking melanosome positioning and acidity to the Wnt/β-catenin signaling pathway.

This review discusses various techniques for depigmentation in vitiligo patients and suggests that cryotherapy, performed by an experienced professional, may be the most cost-effective and accessible method.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

This article discusses hair and nail research contributions in dermatology but reports no new clinical findings.

This article discusses dermatological issues associated with black skin, such as postinflammatory pigmentation and keloids, and highlights the need for practitioners to understand these racial characteristics; it reports no new clinical results.

This study found that incorporating collagenase type I into a noncultured hair follicle cell suspension technique improved cell yield and enhanced repigmentation in patients with stable vitiligo compared to dermabrasion alone.

In this study, loss of the Notch ligand Jag2 in mouse epidermal cells disrupted early differentiation and affected the structure and behavior of adjacent melanocytes, highlighting Jag2's role in epidermal differentiation and tissue homeostasis.

This study investigated novel genetic tools to manipulate hair follicle compartments in mice and found that altering dermal papilla genes can significantly impact hair pigmentation.

In this study, mice lacking the Mcpip1 gene in their myeloid cells did not develop SCC-like tumors but instead showed increased melanocyte activity and hair loss, indicating a distinct role for myeloid Mcpip1 in skin cancer development compared to keratinocyte Mcpip1.

In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.

This review highlights the possibility of safely altering hair color through innovative cosmetics by targeting key biological processes in hair follicles, using insights from mammalian pigmentation studies and drug-induced hair color changes as potential pathways.

This review discusses surgical treatments for vitiligo, emphasizing the importance of proper preparation of the recipient site to improve cosmetic outcomes, while highlighting ongoing research and trials.

This study concluded that THC and THCA incorporate into hair by a mechanism independent of hair pigmentation, likely influenced by indirect deposition via sebum and skin.

This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

This study explored the diversity of melanocyte stem cell subpopulations in the hair follicles of adult female mice and identified novel groups with distinct immune privilege regulation, suggesting a heterogeneous landscape that future research should consider.