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    Glossary Phototoxicity

    skin reaction from sunlight exposure to certain chemicals

    Phototoxicity refers to a skin reaction that occurs when certain chemicals or medications on the skin are exposed to sunlight, leading to damage. This can result in redness, inflammation, and sometimes blistering, similar to a severe sunburn. For professionals, it's important to note that phototoxic reactions are typically caused by the interaction of ultraviolet (UV) light with photosensitizing agents, which can be found in some topical treatments, systemic medications, or even certain plant compounds.

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    Research 30 of 201

    1. Rational Design and Synthesis of 4-((1<i>R</i>,2<i>R</i>)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications Journal of medicinal chemistry · 2008 · 23 citations
    2. Characterization of Cutaneous Photoxicity Induced by Topical Alpha-Terthienyl and Ultraviolet A Radiation Journal of Investigative Dermatology · 1986 · 22 citations
    3. Adverse effects of voriconazole: Over a decade of use 2016 · 100 citations
    4. Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents Drugs · 2019 · 90 citations
    5. The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells Pharmaceuticals · 2021 · 48 citations
    6. Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 11 citations
    7. Human Dermal Safety Studies with Eflornithine HCl 13.9% Cream (Vaniqa™), a Novel Treatment for Excessive Facial Hair Current Medical Research and Opinion · 2000 · 3 citations
    8. Advance and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System Pharmaceutics · 2023 · 2 citations
    9. High-risk cutaneous squamous cell carcinoma in a Japanese allogeneic bone marrow transplant recipient on long-term voriconazole The Journal of Dermatology · 2017 · 2 citations
    10. Systemic Antifungals Springer eBooks · 2018
    11. Photosensitized 2-amino-3-hydroxypyridine-induced mitochondrial apoptosis via Smac/DIABLO in human skin cells Toxicology and applied pharmacology · 2016 · 10 citations
    12. Analysis of accumulation and acute phytotoxic reactions of Ocimum basilicum to lead contamination in the initial phases of plant development The Agrarian Scientific Journal · 2023 · 1 citations
    13. Live imaging of skin immunity using two-photon microscopy: a short review Inflammation and Regeneration · 2026
    14. Fluorescence Microscopy—An Outline of Hardware, Biological Handling, and Fluorophore Considerations Cells · 2021 · 97 citations
    15. Light Sheet Fluorescence Microscopy Quantifies Calcium Oscillations in Root Hairs of<i>Arabidopsis thaliana</i> Plant and Cell Physiology · 2017 · 56 citations
    16. Dermatologic research techniques CRC Press eBooks · 1996 · 33 citations
    17. Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection Cell Transplantation · 2024 · 13 citations
    18. Dermatologic therapy: December 1987 to December 1988 Journal of The American Academy of Dermatology · 1990
    19. Dermatological drugs and topical agents Side effects of drugs annual · 2004
    20. Drug-Induced Skin, Nail and Hair Disorders Drug Safety · 2007 · 114 citations
    21. The photosensitive patient: could it be pellagra? British Journal of Dermatology · 2011 · 2 citations
    22. A fast and simple FIA-chemiluminescence method for the evaluation of Roselle flowers as scavenger of the free radicals generated by UV irradiated antibiotics Journal of Pharmaceutical and Biomedical Analysis · 2018 · 4 citations
    23. Comparative Effect of Datura Metel Leaf and Flower Extracts for Hair Formulations Natural Products Chemistry & Research · 2021
    24. Book Reviews Australasian Journal of Dermatology · 2000
    25. Acne The New England Journal of Medicine · 2005 · 231 citations
    26. Dermatological adverse events with taxane chemotherapy European Journal of Dermatology · 2016 · 141 citations
    27. Protoporphyrin IX: the Good, the Bad, and the Ugly Journal of Pharmacology and Experimental Therapeutics · 2015 · 138 citations
    28. The histopathologic spectrum of psoriasis Clinics in Dermatology · 2007 · 111 citations
    29. Adverse Cutaneous Reactions to Antipsychotics American Journal of Clinical Dermatology · 2002 · 64 citations
    30. Adverse Reactions to Oral Retinoids An Update Drug Safety · 1993 · 53 citations