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Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

New tests detect finasteride and dutasteride in urine quickly and easily.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Avoid chemical and physical damage to protect hair.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Fungi-produced compounds can change plant root growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.