November 2023 in “International journal of Ayurveda and pharma research” This study prepared and evaluated a polyherbal hair oil using plant-based ingredients, finding that it met standard parameters and effectively addressed hair problems such as growth and dandruff, with FDA approval for clinical use.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
September 2022 in “International journal of pharmaceutical quality assurance” This study concluded that sodium lauryl sulfate is very toxic to hair, damaging its structure, while natural conditioners help protect hair integrity and improve consistency and shine.
June 2022 in “International Journal for Research in Applied Science and Engineering Technology” The research developed a herbal shampoo using extracts from Piper Betel and Psidium Guajava leaves, which showed potential in promoting hair growth and managing hair diseases, while replacing synthetic ingredients with safe natural alternatives.
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.
June 2022 in “International Journal of Advanced Research in Science, Communication and Technology” This study aimed to develop a herbal hair serum to enhance hair growth and prevent hair loss, addressing common issues like extreme hair loss in younger populations caused by lifestyle factors such as stress and dietary habits.
7 citations
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February 1998 in “Polymer journal” This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.
December 2025 in “Journal of Pharma Insights and Research.” This study explains the formulation and evaluation of a natural polyherbal shampoo, which effectively colors hair and provides conditioning without the dermal and systemic toxicity risks of synthetic dyes, offering an effective alternative to conventional products.
July 2026 in “International Research Journal of Modernization in Engineering Technology and Science” This study found that a newly formulated herbal shampoo showed acceptable physicochemical characteristics and effective cleansing properties, suggesting it as a promising alternative to synthetic shampoos.
1 citations
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October 2025 in “Gels” This study demonstrates that pH-responsive nanogels designed with comb-like anionic polymers significantly improved oral delivery of the chemotherapy drug camptothecin, enhancing drug stability in acidic conditions and release in the intestines, with increased cellular uptake and cytotoxic effects against colorectal carcinoma cells.
May 2023 in “Jurnal Penelitian Farmasi & Herbal” In this study, researchers developed cucumber-based hair tonics and tested their physical stability, finding them to be homogenous and meet requirements for color and pH, suggesting potential use as a remedy for hair loss.
May 2023 in “Jurnal farmasi sains dan praktis” In this research on cinnamon and virgin coconut oil hair tonics, F2 and F3 demonstrated stable physical properties and mild irritation potential, while formula 1 remained non-irritating but less stable regarding pH and viscosity.
1 citations
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June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
January 2024 in “Indonesian Journal of Pharmaceutical Education” In this experimental laboratory study, three cream formulations containing 1% Caffeine Herbasome® were developed and evaluated for stability, homogeneity, pH, dispersion, and adhesion, with results showing satisfactory stability and suitable adhesion properties for skin application.
February 2024 in “Jurnal Kesehatan Yamasi Makassar” This study in South Sulawesi Province developed a shampoo using ethanol extract from Pondoh salak fruit peel, which met physical stability tests and demonstrated strong inhibitory effects against Staphylococcus epidermidis and Candida albicans, with formulations ranging from 10% to 20% concentrations.
37 citations
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October 2017 in “Saudi pharmaceutical journal” This study reports that six shampoo brands in Saudi Arabia generally comply with the national specifications, demonstrating good physicochemical properties such as foam stability and pH levels.
3 citations
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October 2018 in “International Journal of Green Pharmacy” This study suggested that an herbal shampoo containing Piper betle and Psidium guajava leaves extract may promote hair growth due to its antioxidant properties and showed stability for two months.
This study suggests that a candlenut oil nanoemulsion formulation could enhance hair growth activity in Sprague Dawley rats, with stability for up to 14 days at room temperature.
17 citations
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January 2016 in “Journal of Drug Delivery” In this study, PEG and keratin scaffolds selectively influenced protein release rates based on charge and size, suggesting their potential for targeted delivery of protein therapeutics.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated a polyherbal hair oil containing natural ingredients like Amla and Neem, evaluating it for properties such as pH, stability, and skin irritation, and found it showed satisfactory physical appearance, stability, and enhanced conditioning without irritation.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that a polyherbal hair oil formulation using natural ingredients like Amla, Neem, and hibiscus showed good stability, acceptable pH, and no skin irritation while enhancing hair conditioning properties.
April 2026 in “International Journal for Research in Applied Science and Engineering Technology” In this study, the developed polyherbal shampoo with Hibiscus rosa-sinensis exhibited good stability and cleansing properties, suggesting it may be an effective natural alternative to synthetic anti-hair fall products.
April 2026 in “International Journal of Drug Delivery Technology” In this study, researchers developed and tested a polyherbal dry powder shampoo using natural ingredients like Neem and Aloe vera, reporting good foaming ability, appropriate pH, no skin irritation, and stability, suggesting it as a safe and affordable alternative to synthetic shampoos.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
January 2026 in “Journal of Innovative and Creativity (Joecy)” This study investigated hair growth tonics made with celery leaf extract and found that 4% and 9% concentrations maintained better cyclic stability than 14%, supporting their potential use in herbal cosmetic development due to favorable physicochemical stability.
10 citations
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June 2014 in “Journal of Pharmacy and Pharmacology” This study found that antiandrogenic compounds in Curcuma aeruginosa, including germacrone, degrade rapidly at high temperatures but are more stable when solubilized in PEG-40.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
May 2026 in “DergiPark (Istanbul University)” In this study, researchers successfully scaled a plant-based shampoo formulation for dry and damaged hair from laboratory to industrial production, maintaining its physicochemical properties and microbiological safety throughout, highlighting the formulation's scalability and the importance of quality control in cosmetic manufacturing.
November 2025 in “International Journal of Advanced Research in Science Communication and Technology” In this study, researchers developed an herbal shampoo with natural extracts, showing it has good quality and suitable physicochemical properties like pH, foam stability, and conditioning, making it appropriate for commercial use to help prevent hair loss and maintain hair conditioning.
May 2023 in “Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis” This study found that royal jelly extract, popular for surgical wound healing, contains stable levels of flavonoids and phenols for up to 28 days.