research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
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research Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
research Topically Applied Minoxidil in Baldness
Minoxidil helps hair growth, but results vary.
research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia
PRFM may help treat hair loss, especially in mild cases.
research Anisotrichosis: A Novel Term to Describe Pattern Alopecia
The document suggests "anisotrichosis" as a new term for hair thickness variation in common baldness.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research The Pathophysiology of Delayed Ejaculation
Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.
research Generalized Hypertrichosis After Treatment With Topical Minoxidil
Too much topical minoxidil can cause excessive hair growth, but stopping treatment reverses it.
research Platelet-Rich Plasma: Principles and Applications in Plastic Surgery
Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
research Use of Metformin in Pediatric Age
Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
research Fibrosing Alopecia in a Pattern Distribution
Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
research Bilateral Eyelid Pseudoptosis From Lipogranulomas of the Preaponeurotic Fat Pads
Surgical removal of abnormal fat pads fixed the woman's eyelid issue caused by likely silicone injections.
research Androgenic Alopecia in Females: Diagnosis and Treatment
The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.
research Hirsutism in Adolescent Females
The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
research Glutamic Acid Promotes Hair Growth in Mice
Glutamic acid helps increase hair growth in mice.
research Synthetic Studies Toward the Development of Novel Minoxidil Analogs and Conjugates with Polyamines
New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
research Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research Development and Validation of RP-HPLC Method for Simultaneous Estimation of Minoxidil and Aminexil in Topical Formulation
A new method was created to accurately measure minoxidil and aminexil in hair loss treatments.
research Dexpanthenol May Be a Novel Treatment for Male Androgenetic Alopecia: Analysis of Nine Cases
Dexpanthenol improves hair growth in male baldness.
research Hair Root Studies in Patients Suffering from Primary and Secondary Syphilis
Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.
research Leprosy on the Scalp: A Case Report
A man from Brazil had a rare case of leprosy on his scalp, which improved with treatment.
research Therapeutic Synergy Between Contact Dermatitis from a Wig-Fixing Device and Tofacitinib on Alopecia Areata
A man's hair regrew from alopecia areata after using tofacitinib and experiencing contact dermatitis from a wig device.
research Possible Immunomodulating Effect of Retinol on Cytokine Secretion in Patients with Recurrent Furunculosis
Retinol may affect immune responses in people with frequent skin boils.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research A Man with Changes on Nose
The document discusses a condition causing hair loss after surgery and a type of rosacea affecting the nose, with treatments including surgery and laser therapy.
research British Menopause Society Tools for Clinicians: Testosterone Replacement in Menopause
Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.