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Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

Long-term parenteral nutrition without zinc can cause severe zinc deficiency.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.