research Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing
A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
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480-510 / 1000+ results research Alternative Therapies in Vitiligo
Some alternative treatments for vitiligo show promise but need more research to confirm their safety and effectiveness.
research Uptake and Utilisation of Amino Acids by Human Hair Follicles and Related Cells
This study investigated the role of amino acids in human hair follicles, focusing on cysteine and arginine. It found that both amino acids were essential for hair growth and protein synthesis. Cysteine influenced hair fiber diameter, with reduced supply leading to thinner fibers and slower growth. Hair follicles utilized the amino acid transporter ASC for cysteine uptake, while arginine was primarily incorporated into proteins in the hair root sheaths and fibers. Arginine also affected energy metabolism, as its availability influenced lactate production. The study noted that hair follicles did not express certain peptide transporters and suggested a slower mechanism for glutamate transport compared to other amino acids.
research Neonatal Inhibition of Androgen Activity Alters the Programming of Body Weight and Orexinergic Peptides Differentially in Male and Female Rats
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
research Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Affect Stem Cells in Human Scalp Hair Follicles
Fish-derived collagen may help hair grow longer and affect hair stem cells, while bovine collagen could benefit hair stem cell maintenance, potentially aiding in hair loss conditions.
research Infectious Diseases 2015: The Antimicrobial Peptides Delivery Strategies Based on Nanotechnology to Treat Infectious Diseases
Nanotechnology can effectively deliver antimicrobial peptides for treating infections.
research Mutational Landscape of Extramammary Paget Disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
research Age-Dependent Loss of the Stemness and Antimicrobial Defense Function of Dermal Fibroblasts Is Mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research A Randomized Study of Biomimetic Peptides Efficacy and Impact on the Growth Factors Expression in the Hair Follicles of Patients with Telogen Effluvium
Biomimetic peptides improved hair growth and increased growth factors in hair follicles for hair loss patients.
research The New Approach to Early Diagnosis of Adenomyosis
A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.
research Clinical Snippets: Stabilization of Vitamins C and E, Hedgehog Pathway Agonists, Atopic Dermatitis, Lentigo Maligna Melanoma, and Relaxin-Deficient Mice
Ferulic acid helps stabilize vitamins C and E for better skin protection from the sun, certain compounds may promote hair growth, atopic dermatitis patients have lower skin defense molecules, older men are more likely to get a type of skin cancer, and a substance called relaxin may prevent age-related skin thickening.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro
A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
research QR678 and QR678 Neo Hair Growth Formulations: A Cellular Toxicity and Animal Efficacy Study
QR 678 and QR 678 Neo are safe and promote hair growth, potentially helping chemotherapy-induced hair loss.
research Therapeutic Response of Androgenetic Alopecia After Digital Drug Delivery with Application of Prodew 500®, Nanofactor® aFGF, Nanofactor® VEGF, Copper Peptide®, Prohairin B4®, Capillisil HC® and Arct-Alg®
The document does not give specific results for hair loss treatment effectiveness.
research Dietary Isoflavone Increases Insulin-Like Growth Factor-I Production, Thereby Promoting Hair Growth in Mice
Eating isoflavone can help mice grow hair by increasing a growth factor.
research Review of Systemic Methotrexate Therapy in Pediatric Dermatoses
Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.
research Current Possible Treatment Approaches of Polycystic Ovary Syndrome (PCOS)
Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.
research In Vitro Hair Growth-Promoting Effect of Lgr5-Binding Octapeptide in Human Primary Hair Cells
A synthetic octapeptide may help promote hair growth and counteract hair loss.
research Induction of Human Hair Growth Using Vascularized 3D Hair Follicle Constructs
Researchers created a 3D-printed skin model that grew human hair when grafted onto mice by improving blood supply to the grafts.
research Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle
Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
research Short-Term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin
Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Increased Hair Polyamine Levels in Patients with Alzheimer's Disease
Alzheimer's patients have higher levels of certain chemicals in their hair.
research Characterization of a Mouse Scube3 Reporter Line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research The Impact of Obesity on the Folliculosebaceous Unit
Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.
research Cloning, Computational Analysis and Expression Profiling of Steroid 5 Alpha-Reductase 1 (SRD5A1) Gene During Reproductive Phases and Ovatide Stimulation in Endangered Catfish, Clarias Magur
The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
research LO-010 Relationship Between The EULAR/ACR Classification Criteria And Organ Damage In Systemic Lupus Erythematosus
Higher EULAR/ACR scores in SLE patients predict more organ damage.
research Responsiveness of the CLASI to Alopecia and Mucous Membrane Involvement: A Retrospective Study of Prospectively Collected Data
Excluding alopecia and mucous membrane components from the CLASI-A score reduces its effectiveness in capturing important disease activity.