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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

Uterine transplants for transgender women are feasible but need more research.

Finasteride reduces prostate cancer risk but may increase high-grade tumors and has side effects; biopsy methods have similar outcomes; psychosocial factors affect sexual recovery post-surgery.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Udenafil may help hair grow by activating certain stem cells.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

More hair loss leads to higher risk of psychosexual disorders, especially in women.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

A 15-year-old girl has a skin condition causing blisters on her feet, likely inherited from her family.

Toe Tourniquet Syndrome is often misdiagnosed.

Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.

Scalp involvement is common in pemphigus and can lead to hair loss, with the severity of scalp lesions linked to overall disease severity.