March 2026 in “SKIN The Journal of Cutaneous Medicine” This study found that ritlecitinib was well tolerated in children aged 6 to under 12 years with severe alopecia areata, with ongoing trials examining its efficacy and safety over a 24-week period and in long-term use up to 36 months.
March 2026 in “Skin Appendage Disorders” This narrative review highlights the distinct needs of pediatric hair care, emphasizing gentler formulations due to differences in children's hair physiology, structure, and barrier function, and calls for targeted regulations and research due to limited safety evidence.
This review highlights the potential of microneedles as a pediatric-friendly method for delivering proteins, vaccines, and diagnostics transdermally, noting their ability to penetrate the skin's barrier and suggesting future applications in other parts of the body.
March 2026 in “Journal of Investigative Dermatology” This quality improvement initiative at Children’s Hospital of Orange County seeks to increase awareness and use of nonprofit pediatric wig programs by at least 50% over three months through educational interventions.
March 2026 in “Journal of Investigative Dermatology” Early diagnosis and tailored treatment are crucial to prevent permanent hair loss and support self-esteem in children with scarring alopecia.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This case report describes a 7-year-old girl who developed radiation-induced alopecia after a neurointerventional procedure, with dermoscopy revealing specific hair and scalp patterns that helped diagnose this rare complication. The findings highlight the importance of dermoscopy in distinguishing RIA from other alopecic disorders in children.
January 2026 in “International Journal of Dermatology” This article discusses the development of the Alopecia Areata Children's Quality of Life Index and highlights its potential importance for assessing the psychosocial burden in pediatric cases, without providing clinical results.
January 2026 in “Pediatria Polska” In this case series, five pediatric patients with tinea capitis showed varied clinical presentations, emphasizing the need for early diagnosis and prompt systemic antifungal therapy to prevent permanent outcomes such as alopecia and scarring.
January 2026 in “Annals of Dermatology” In this study, 80% of pediatric patients with alopecia areata treated with calcipotriol/betamethasone ointment showed hair regrowth over 12 weeks, suggesting it may be an effective option, though 20% had no improvement or worsening symptoms.
November 2025 in “Journal of Pharmacy and Pharmacology” This review highlights pigment epithelium-derived factor's roles in ageing and development, focusing on its antioxidant functions and support of stem cell survival, but reports no new experimental results.
November 2025 in “Mendeley Data” This study found that tofacitinib and baricitinib, when administered with unorthodox weight-stratified dosing in pediatric patients with moderate-to-severe AA, showed comparable efficacy and tolerability, though baricitinib's efficacy decreased with non-standard dosing.
October 2025 in “Pediatric Dermatology” This report describes how ultraviolet-induced fluorescence dermoscopy helped accurately diagnose scalp disorders, specifically alopecia areata and tinea capitis, in pediatric patients.
August 2025 in “American Journal of Case Reports” In this case report, researchers describe a 13-year-old phenotypic female with 46,XY karyotype, previously misdiagnosed with androgen insensitivity syndrome, who was later identified to have 17-beta-hydroxysteroid dehydrogenase type 3 deficiency, underscoring the importance of genetic and hormonal tests for accurate diagnosis of sex development disorders.
July 2025 in “Journal of Investigative Dermatology” In this study, higher expression of PEDF was observed in hair follicles from balding regions in AGA patients, suggesting that targeting PEDF could be a promising approach for treating androgenetic alopecia.
July 2025 in “Pediatric Transplantation” In this case study, a rare viral infection called trichodysplasia spinulosa was diagnosed in a 10-year-old girl post-kidney transplant; she was treated successfully with reduced immunosuppression alongside leflunomide and valganciclovir, though the efficacy of valganciclovir remains uncertain.
July 2025 in “International Journal of Homoeopathic Sciences” In this case study, an 8-year-old girl with complete hair loss on her head was successfully treated with individualized homoeopathic medicine, Natrum Muriaticum, over four months, suggesting a positive role for homoeopathy in treating alopecia areata.
July 2025 in “Journal of Ayurveda Case Reports” This case report describes a five-year-old boy with Alopecia Universalis who did not respond to allopathic treatments but showed significant hair regrowth after two months of Ayurveda therapies, suggesting their potential effectiveness for this condition.
June 2025 in “Scholars Journal of Medical Case Reports” This case report highlights that trichoscopy facilitated early diagnosis of discoid lupus erythematosus of the scalp in a 9-year-old boy, with oral prednisone minipulse therapy leading to complete remission and hair regrowth.
June 2025 in “Pediatric Annals” This review highlights the importance of primary care physicians in diagnosing and managing hair loss in adolescents, noting that early treatment and education are essential for achieving the best clinical and psychosocial outcomes.
April 2025 in “BMC Urology” This case report highlighted a rare occurrence of both adrenocortical carcinoma and uric acid kidney stones in a 5-year-old boy, with hormonal levels and clinical symptoms returning to normal after treatment and no recurrence over four years, emphasizing comprehensive endocrine evaluations in pediatric ACC management.
April 2025 in “Dermatology The American Medical Journal” Low-dose isotretinoin is effective for treating pediatric scarring alopecia.
April 2025 in “Düzce Tıp Fakültesi Dergisi” In this study, researchers examined vitamin D levels and blood count parameters in children and adolescents with non-scarring alopecia, finding significant vitamin D deficiency but no significant differences in deficiency or insufficiency across different types of alopecia.
February 2025 in “Pediatric Dermatology” This study suggests that permanent chemotherapy-induced alopecia can occur in pediatric patients with Ewing's sarcoma and that treatments like minoxidil could be beneficial, though may not lead to full hair regrowth.
February 2025 in “The Indian Journal of Pediatrics” Siddha therapeutics successfully treated a 14-year-old's alopecia areata, leading to full hair regrowth without side effects.
February 2025 in “Journal of the American Academy of Dermatology” Standardized treatment protocols are needed for children with androgenetic alopecia.
January 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This study surveyed German dermatologists about treating children and adolescents with alopecia areata, revealing significant emotional challenges like bullying and low self-esteem, dissatisfaction with available treatments, and a need for both psychological support and new therapeutic guidelines.
In this analysis, JAK inhibitors were found to provide clinically meaningful and durable hair regrowth in pediatric alopecia areata, outperforming traditional therapies with a manageable safety profile.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study found that oral tofacitinib significantly reduced alopecia severity and improved quality of life over 12 months for children with moderate to severe alopecia areata, though the authors recommend more research due to the small sample size and absence of a control group.
July 2024 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This study highlights the importance of identifying the various causes of hair loss in children to enable accurate diagnosis and management, emphasizing that proper treatment, including psychosocial support, can prevent a decline in their quality of life.
July 2024 in “Journal of Investigative Dermatology” Topical corticosteroids are recommended first for treating pediatric alopecia areata due to safety and ease of use.