13 citations
,
November 2021 in “Pediatric Dermatology” This study found that oral tofacitinib was effective and well tolerated for treating alopecia areata in most pediatric patients, with nearly 73% experiencing hair regrowth.
13 citations
,
July 2016 in “Pediatric Dermatology” This study found that loose anagen syndrome was more common in females and observed across all hair colors and skin types.
13 citations
,
March 2014 in “Pediatric Dermatology” This case report observed that a 2-year-old girl with loose anagen hair syndrome experienced rapid and significant improvement without adverse effects from tapered minoxidil 5% treatment over 28 months.
12 citations
,
March 2015 in “Pediatric Dermatology” This review discusses diagnostic and management challenges of polycystic ovary syndrome in children and adolescents and reports no new clinical results; it emphasizes early intervention when a provisional diagnosis is suspected.
11 citations
,
July 2019 in “Pediatric dermatology” In this study, empty follicular openings and pigtail hairs were more frequently observed in children with alopecia areata compared to adults, while yellow dots were less common in children.
11 citations
,
October 2016 in “Pediatric dermatology” This case study observed that three girls with alopecia experienced complete hair regrowth after avoiding balsam of Peru and related fragrances, suggesting contact allergy played a role in their hair loss.
9 citations
,
October 2013 in “Pediatric dermatology” This study highlights a dissecting cellulitis-like presentation of tinea capitis in children that should be identified to ensure correct diagnosis and treatment to prevent scarring alopecia.
8 citations
,
September 2016 in “Pediatric dermatology” This review discusses the diverse clinical manifestations of mucopolysaccharidoses in children and emphasizes the importance of early diagnosis and treatment initiation, but it reports no new clinical findings.
8 citations
,
August 2013 in “Pediatric Dermatology” This article reviews loose anagen hair syndrome, an inheritable hair disorder affecting children and sometimes adults, but does not report any new clinical results.
6 citations
,
October 2016 in “Pediatric Dermatology” This case report describes a unique instance of a 6-year-old girl developing angioedema after treatment with squaric acid dibutylester for alopecia areata.
5 citations
,
March 2025 in “Pediatric Dermatology” This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.
5 citations
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February 2025 in “Pediatric Dermatology” In this study, ritlecitinib was generally well tolerated in pediatric alopecia areata patients aged 6 to <12 years, with no severe or serious adverse events reported, and the drug's pharmacokinetic parameters were successfully characterized.
5 citations
,
July 2024 in “Pediatric Dermatology” This study reports that dupilumab significantly reduced alopecia areata severity in pediatric patients with atopic dermatitis, indicating potential as an effective treatment option, though further research on long-term safety and optimal use is needed.
5 citations
,
June 2014 in “Pediatric dermatology” This case report details how a 9-month-old girl's generalized hypertrichosis developed following exposure to 5% topical minoxidil via her grandfather's use, which resolved after removing the exposure.
4 citations
,
March 2025 in “Pediatric Dermatology” This review examines the clinical presentation of alopecia areata in children and compares it to adult-onset cases, noting that data on pediatric cases is scarce and often varies, with reported onset typically between ages 6 and 12.
4 citations
,
August 2021 in “Pediatric dermatology” This study concluded that biotin, alone or combined with topical minoxidil, may effectively treat short anagen syndrome in children by enhancing anagen duration.
4 citations
,
May 2017 in “Pediatric Dermatology” This case report details a 3-year-old girl with short anagen syndrome, characterized by short, sparse hair, where X-ray microanalysis showed her hair's main bioelements were normal.
4 citations
,
August 2013 in “Pediatric dermatology” This report describes an 11-year-old girl with peripilar keratin casts, a condition often underdiagnosed and mistaken for nits, highlighting the usefulness of keratolytic treatments in management.
3 citations
,
December 2024 in “Pediatric Dermatology” This review discusses the clinical and histopathologic features of pediatric lichen planopilaris and reports therapeutic responses to various treatments; the condition should be considered in cases of patchy hair loss in children.
3 citations
,
November 2024 in “Pediatric Dermatology” This study found that dermatologic adverse events are common in children taking MEK inhibitors, with selumetinib patients experiencing less severe reactions and a lower risk of dosage adjustments. Age was noted as a factor in the likelihood of specific skin reactions.
3 citations
,
August 2023 in “Pediatric dermatology” This study reviewed medical treatments for hidradenitis suppurativa in children and found that treatment response was high across several therapies, but the evidence is limited to case reports and series, necessitating more prospective studies for clearer efficacy and safety conclusions.
3 citations
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May 2023 in “Pediatric Dermatology” This case report describes a 9-year-old boy with atypical alopecic and aseptic nodules of the scalp, suggesting possible inclusion within the spectrum of typical AANS and DCS due to its prepubertal onset and facial involvement.
3 citations
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September 2017 in “Pediatric Dermatology” This article discusses contact dermatitis linked to alopecia and hyperpigmentation, but it reports no new clinical results.
3 citations
,
March 2017 in “Pediatric Dermatology” This case report documents the first known instance of FOXN1 duplication linked to congenital hypertrichosis.
3 citations
,
September 2016 in “Pediatric Dermatology” This case study reports that hypertrichosis, although not always present, may be an important diagnostic clue for superficial epidermolytic ichthyosis in a young child.
3 citations
,
February 2016 in “Pediatric dermatology” This report describes two cases of Rapp–Hodgkin ectodermal dysplasia where refractory scalp erosions improved significantly with potent topical steroids; it also suggests a potential link between these scalp conditions and erosive pustular dermatosis of the scalp in elderly patients.
3 citations
,
May 2013 in “Pediatric Dermatology” This case report documents the second known instance of a salivary gland choristoma on the chest wall of a newborn, highlighting its benign nature and the importance of accurate diagnosis.
2 citations
,
April 2025 in “Pediatric Dermatology” This study identified and described a new form of alopecia termed "macular alopecia," predominantly affecting young Hispanic/Latinx females, characterized by small macules on the scalp with a high rate (63%) of spontaneous resolution in about five months.
2 citations
,
March 2024 in “Pediatric Dermatology” This case report described two siblings with uncombable hair syndrome characterized by unique hair features, and identified a new pathogenic variant in the PADI3 gene (c.1374dup; p. Val459ArgfsTer15) not previously documented.
2 citations
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July 2022 in “Pediatric dermatology” This case report highlights that a restrictive rice milk diet in a young child led to kwashiorkor with severe malnutrition, skin changes, and developmental regression, which improved with a protein-rich therapeutic diet.