Short Anagen Syndrome: A Case Series and Algorithm for Diagnosis

August 2021 in “ Pediatric dermatology ”

Michela Starace, Carlotta Gurioli, Miriam Anna Carpanese, Francesca Bruni, Bianca Maria Piraccini, Annalisa Patrizi, Aurora Alessandrini

short anagen syndrome anagen phase telogen phase biotin minoxidil Rogaine

TLDR Biotin, alone or with minoxidil, effectively treats short anagen syndrome.

The study on short anagen syndrome (SAS) involved a retrospective review of 25 pediatric patients at the University of Bologna's Dermatology Department. SAS is characterized by a short anagen phase, primarily affecting Caucasian children, and results in an inability to grow long hair. Key diagnostic findings included parental reports of no need for haircuts, conical-shaped hair tips, and a higher percentage of thin hair shafts. The mean anagen-to-telogen ratio was 66:34, compared to the normal 90:10. The study developed a diagnostic algorithm for SAS and found that treatments with biotin alone or combined with topical minoxidil were effective.

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research Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy

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Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.

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The study concluded that AAI and DAA are forms of the same disease, with different symptoms in men and women, and that corticosteroid treatment is effective.

research Short Anagen Syndrome: Case Series and Literature Review

13 citations , March 2018 in “Pediatric Dermatology”

Children with short anagen syndrome usually see their hair condition improve as they get older.

research Clinical, Microscopic, and Ultrastructural Findings in a Case of Short Anagen Syndrome

4 citations , May 2017 in “Pediatric Dermatology”

The study found that Short Anagen Syndrome results in short hair growth not due to hair fragility, and hair may grow longer after puberty.

research A Review of the Use of Biotin for Hair Loss

78 citations , January 2017 in “Skin appendage disorders”

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

research Trichoscopy Findings in Loose Anagen Hair Syndrome: Rectangular Granular Structures and Solitary Yellow Dots

18 citations , March 2015 in “Journal of Dermatological Case Reports”

Rectangular black granules, solitary yellow dots, and mostly single-hair follicles suggest Loose Anagen Hair Syndrome.

research Short Anagen Syndrome in a Girl with Curly Dark Hair and Consanguineous Parents

5 citations , December 2012 in “Journal of the American Academy of Dermatology”

A 3-year-old girl has short anagen syndrome, causing her hair to stay short.

research Short Anagen Syndrome in an Indian Woman and Its Impact on Quality of Life

2 citations , January 2012 in “International Journal of Trichology”

An Indian woman with Short Anagen Syndrome had very short hair and a lower quality of life.

research Short Anagen Syndrome

28 citations , March 2011 in “Pediatric dermatology”

Short anagen syndrome causes short hair that may grow longer after puberty.

research Short Anagen Syndrome in an African American Woman

10 citations , December 2010 in “Journal of The American Academy of Dermatology”

A 38-year-old African American woman has a rare condition that prevents her from growing long hair.

research Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome

46 citations , October 2009 in “Archives of Dermatology”

Loose anagen hair syndrome, often affecting young girls, can be diagnosed with a hair-pull test and usually gets better on its own, but severe cases may need treatment.