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Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

AMT may cause hair loss and changing dWAT activity could help treat it.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.

Finasteride helps female-pattern hair loss.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.

AGEs may cause hair loss by increasing inflammation in hair follicles.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.