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Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Androgens and other hormones affect hair growth and skin conditions like acne.

High aldosterone and free testosterone levels link to female hair loss; testing aldosterone may predict hypertension risk.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Fat cells in the skin help start healing and form important repair cells after injury.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.