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Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Noggin is necessary to start the hair growth phase in skin after birth.

PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lactate production is important for activating hair growth stem cells.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Some medicinal plants can help heal wounds and may lead to new treatments.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Latanoprost can make eyelashes longer, thicker, and darker.

Blocking JAK-STAT signaling can lead to hair growth.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Cathepsin L is essential for normal hair growth and development.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.