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Glossary Ovulation Induction

medical treatment stimulating ovaries to release eggs

Ovulation Induction is a medical treatment designed to stimulate the ovaries to produce and release eggs, typically used in women who have irregular or absent ovulation. This process often involves the administration of medications such as clomiphene citrate or gonadotropins to encourage the development of one or more mature follicles, thereby increasing the chances of conception.

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Insulin Sensitizer Agents Alone and in Co-Treatment with Recombinant FSH for Ovulation Induction in Women with PCOS

research Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women

75 citations , November 2009 in “Gynecological Endocrinology”

This study found that both myo-inositol and metformin helped restore normal menstrual cycles in patients with PCOS, but myo-inositol appeared to be more effective in inducing pregnancy.

research Contemporary medical therapy for polycystic ovary syndrome

31 citations , September 2006 in “International journal of gynaecology and obstetrics”

This article reviews diagnostic criteria and treatment options for polycystic ovary syndrome, focusing on hormonal and metabolic management strategies, and presents no new clinical data.

A Modern View of Polycystic Ovarian Syndrome

research A MODERN VIEW OF THE POLYCYSTIC OVARIAN SYNDROME

January 2020

This article discusses the challenges of diagnosing and managing polycystic ovarian syndrome and reports no new research findings, emphasizing the need for improved diagnostic criteria and lifestyle intervention to prevent complications.

research Letrozole-Assisted Ovulation Induction Combined with Lifestyle Modification in Women with PCOS: A Review

January 2026 in “Journal of Education Health and Sport”

This review assesses whether using letrozole alongside physical activity and nutrition is clinically beneficial for enhancing ovulation outcomes in women with PCOS-related infertility, but it doesn't report specific results from the evaluation.

research Infertility: Evaluation and Initial Management

5 citations , October 2012 in “Journal of Midwifery & Women's Health”

This article reviews infertility diagnosis and initial management for advanced practice clinicians, emphasizing the role of midwives and advanced practice nurses, but reports no new clinical findings.

research The treatment of polycystic ovary syndrome.

17 citations , February 2004 in “PubMed”

This review discusses symptom-driven treatment approaches for PCOS, focusing on ovulation induction, androgen reduction, and weight management, and reports recent advances like recombinant FSH and GnRH-agonist protocols without providing new clinical results.

research Diagnosis and Management of Infertility due to Anovulation

2 citations , March 2011 in “Infertility”

This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.

research Comprehensive clinical management of polycystic ovary syndrome.

4 citations , June 2007 in “PubMed”

This review discusses current strategies for diagnosing and treating polycystic ovary syndrome and reports no new clinical results.

research Depo-Provera: an injectable contraceptive.

January 1982 in “PubMed”

This article reviews the contraceptive agent Depo-Provera, discussing its effectiveness, potential side effects, and safety concerns, but reports no new clinical results.

research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome

18 citations , December 2014 in “Obstetrics and Gynecology Clinics of North America”

This study suggests that weight loss can improve fertility outcomes in overweight and obese women with PCOS, and letrozole should be considered the new first-line treatment over clomiphene citrate for anovulatory infertility in this population.

An Update of Polycystic Ovary Syndrome: Causes and Therapeutic Options

research An update of polycystic ovary syndrome: causes and therapeutics options

5 citations , October 2022 in “Heliyon”

This review discusses infertility in polycystic ovary syndrome and therapeutic options, without reporting new results; it underscores the importance of personalized treatment plans based on patient needs and disease characteristics.

research Clomiphene Citrate versus Letrozole for Ovulation Induction in PCOS: A Comparative Study

3 citations , January 2018 in “Journal of South Asian Federation of Obstetrics and Gynaecology”

This study compared letrozole and clomiphene citrate for ovulation induction in women with polycystic ovary syndrome and found that while clomiphene led to more follicles, monofollicular development and endometrial thickness were higher with letrozole, and pregnancy rates did not significantly differ between the two treatments.

Reconsideration of Guidelines for Metformin Use in Ovulation Induction for PCOS by ESHRE and ASRM

research The guidelines issued by the European Society for Human Reproduction and Embryology and the American Society for Reproductive Medicine regarding the induction of ovulation with metformin in patients with the polycystic ovary syndrome potentially require reconsideration

11 citations , April 2013 in “Hormones”

This article reviews recent data suggesting that metformin may be beneficial for anovulatory PCOS patients with normal BMI and clomiphene resistance but emphasizes that more studies are needed to confirm these findings.

A Randomized Cohort Study: Is It Worth the Time to Receive Antiandrogenic Pretreatment Before Ovulation Induction for Women With Polycystic Ovary Syndrome?

research A Randomized Cohort Study: Is It Worth the Time to Receive Antiandrogenic Pretreatment Before Ovulation Induction for Women With Polycystic Ovary Syndrome?

2 citations , February 2022 in “Frontiers in Endocrinology”

This study found that antiandrogenic pretreatment with combined oral contraceptives did not improve ovulation and pregnancy outcomes compared to direct letrozole induction in women with PCOS.

research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome

32 citations , July 2001 in “Endocrine Practice”

This review discusses the therapeutic use of insulin-sensitizing agents in polycystic ovary syndrome, reporting improved ovulation, insulin sensitivity, and reduction of hyperandrogenism, but calls for larger studies to confirm these effects.

Optimal Starting Dose of Clomiphene Citrate for Ovulation Induction in Anovulatory PCOS Women

research How to Choose the Optimal Starting Dose of Clomiphene Citrate (50 or 100 mg per Day) for a First Cycle of Ovulation Induction in Anovulatory PCOS Women?

July 2023 in “Journal of Clinical Medicine”

In this study, researchers investigated factors predicting resistance to clomiphene citrate in women with anovulatory PCOS, identifying AMH and SHBG levels as significant indicators, but they found no reliable thresholds for predicting resistance to the standard 50 mg/day dose.

research The role of metformin in the management of polycystic ovary syndrome

7 citations , November 2003 in “Current Opinion in Obstetrics & Gynecology”

This review summarizes recent studies on metformin for polycystic ovary syndrome, reporting its beneficial effects on endocrine, metabolic, and reproductive outcomes, but highlights ongoing debate about its mechanisms.

research Current evaluation of amenorrhea

38 citations , October 2006 in “Fertility and Sterility”

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome (PCOS)

18 citations , March 2014 in “Current Pharmaceutical Biotechnology”

This review discusses metformin's use in women with polycystic ovary syndrome, focusing on benefits during pre-conception and pregnancy, but reports no new clinical results.

Update: The Pathogenesis and Treatment of Polycystic Ovary Syndrome

research Update: The Pathogenesis and Treatment of PCOS

11 citations , July 2003 in “The Nurse practitioner”

This article reviews diagnostic and management strategies for polycystic ovary syndrome in primary care and reports no new clinical results; it also discusses when specialist referral is appropriate.

research Management of Polycystic Ovarian Syndrome: Looking Beyond the Ovaries

April 2024 in “Canadian Women s Health Today”

This review suggests that "polycystic ovarian syndrome" is a misleading name, as the disorder involves complex metabolic and reproductive issues beyond ovarian dysfunction and may stem from factors affecting the fetus in utero.

research Can serum vaspin levels predict clomiphene resistance in infertile women with PCOS?

7 citations , August 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology”

This study found that lower serum vaspin levels (below 3.74ng/mL) may predict successful ovulation induction with clomiphene citrate in anovulatory women with PCOS, indicating potential resistance when levels are higher.

research Hirsutism-A Comprehensive Update of Embryology, Aetiopathogenesis and Therapeutic Approach

1 citations , February 2017 in “Journal of gynecology and womens health”

This review discusses the causes and management of hirsutism, recommending low-dose oral contraceptives with flutamide over cyproterone-containing preparations, but reports no new clinical findings.

Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

research Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome

6 citations , August 2023 in “Fertility and Sterility”

This review details the 2023 International Guideline update for assessing and managing polycystic ovary syndrome, which provides evidence-based recommendations to improve care and patient outcomes but notes the remaining low to moderate quality of evidence.

research Polycystic Ovarian Syndrome

89 citations , November 2014 in “Medical Clinics of North America”

This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.