22 citations
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January 1999 in “Journal of Toxicology Clinical Toxicology” This report describes the first documented case of an oral overdose of the extra strength 5% minoxidil solution, resulting in severe hypotension and requiring intensive medical intervention.
18 citations
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January 1992 in “The Journal of emergency medicine” This case report describes a 20-year-old female who ingested an unknown quantity of minoxidil tablets in an overdose, presenting with cardiovascular symptoms, but her condition stabilized after supportive care.
This case report details a 61-year-old man's overdose on oral minoxidil, resulting in systemic side effects like hypotension and edema, which resolved without intervention; similar symptoms were observed in 14 other patients after minoxidil ingestion.
June 2016 in “Makedonski medicinski pregled” This case report describes severe hypotension, acute coronary syndrome, tachycardia, and acute kidney failure in a man who ingested topical minoxidil, with eventual recovery following intensive treatment.
February 2023 in “Clinical Toxicology” This letter to the editor raises concerns about minoxidil, an arterial vasodilator also used for androgenic alopecia, noting that overdose can cause severe side effects such as distributive shock, pulmonary edema, and myocardial ischemia.
In this case report, a 23-year-old man experienced dizziness, blurred vision, malaise, and fatigue after excessive use of topical minoxidil for three days, with symptoms resolving once minoxidil was discontinued.
January 2011 in “Reactions Weekly” St. John's Wort may reduce the effectiveness of finasteride by increasing its breakdown in the body.
10 citations
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November 2019 in “American Journal of Tropical Medicine and Hygiene” This case report highlights a patient who developed pancytopenia, transaminase elevation, and alopecia after consuming large amounts of veterinary albendazole purchased online, which he used without medical supervision.
9 citations
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November 2017 in “International Journal of Nanomedicine” This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.
6 citations
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January 2015 in “Indian Dermatology Online Journal” This study observed that an overdose of levothyroxine in a hypothyroid infant led to rapid hair loss, which improved after reducing the medication dose.
December 2023 in “Toxicology communications” This report describes a case of prolonged distributive shock attributed to minoxidil overdose, which involved intentional ingestion alongside trauma and NSAIDs, successfully managed with medications and hydration despite persistent low blood pressure.
January 2017 in “Indian Dermatology Online Journal” This letter discusses the potential role of zinc deficiency in hypothyroid infants with alopecia due to levothyroxine overdose and reports no new results.
March 2026 in “Critical Care Medicine” In this case study, treatment with methylene blue successfully improved blood pressure in a patient with refractory vasodilatory shock due to massive minoxidil ingestion, highlighting its potential as an adjunctive therapy.
March 2024 in “JACCP: journal of the American College of Clinical Pharmacy” Timely, tailored treatment is crucial for managing drug overdoses effectively.
5 citations
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May 1983 in “Australian journal of biological sciences” This study found that concurrent administration of cycloleucine with ethionine prevented the weakening of wool fibers in sheep, whereas reduced glutathione did not have the same effect.
2 citations
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January 2007 in “Toxicologie Analytique et Clinique” This case study observed a massive lithium overdose in a 38-year-old woman with bipolar disorder, who survived despite extremely high lithium concentrations through continuous venovenous hemodiafiltration.
2 citations
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January 2017 in “Journal of nutrition & food sciences” This article explores the concept of cycling synergistic nutrients to minimize overdose risks and enhance nutrient absorption, but presents no new clinical findings; it suggests applicability across various health domains.
June 2024 in “Research Square (Research Square)” This case report documented a 32-year-old man's acute pancreatitis following an overdose of finasteride, highlighting the potential for rare but severe side effects from the drug in overdose situations, and suggesting a need for further research into its safety.
1 citations
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January 2007 in “The Kitakanto Medical Journal” This report documents a case where a man survived sub-acute toxicity from an overdose of the anticancer drug UFT due to effective treatment with antibiotics and granulocyte colony-stimulating factor.
May 2026 in “Sudovo-medična ekspertiza” This study documented three cases of acute thallium poisoning—one involving accidental overdose and two linked to intentional homicide—characterized by neurological and systemic symptoms, and in severe instances, death, underscoring thallium compounds' significant toxicity.
January 2021 in “Universal Journal of Pharmaceutical Research” This study found that methanol extract of Russelia equisetiformis reduced liver damage from paracetamol overdose in rats, suggesting it has a protective effect against hepatic injury.
6 citations
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November 1999 in “Psychiatric services” This case report describes a woman who experienced complete but temporary scalp hair loss after a massive overdose of divalproex, suggesting a potential acute side effect of the drug.
April 2025 in “Suez Canal University Medical Journal” This case report details a 66-year-old male patient who developed eosinophilic pleuro-pericardial effusion likely due to valproic acid toxicity or overdosage, with full recovery observed after medication adjustments at a six-month follow-up.
May 2025 in “Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)” This study found that using platelet-rich plasma in optimal doses improves mesh integration and reduces the risk of chronic pain and fibrosis in hernia repair, but overdoses led to inflammatory complications in rats.
January 2015 in “International Journal of Nanomedicine” In this animal study, the researchers found that administering anionic lipid nanoemulsions called squarticles increased survival rates and mitigated the adverse effects of amitriptyline overdose in rats.
May 2026 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy” This study reported that acute thallium poisoning, investigated through three forensic cases involving both intentional and accidental overdoses, resulted in severe symptoms including neurological damage, multiple organ failure, alopecia, and, in two cases, death, emphasizing the extreme toxicity of thallium compounds.
36 citations
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January 1998 in “Journal of Dermatological Treatment” This study developed a standardized questionnaire to measure patient-perceived changes in hair growth and appearance, which showed significant favoring of active treatment over placebo in a clinical trial for male androgenetic alopecia.
2 citations
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May 2022 in “Cutis” Taking too much Albendazole can cause hair loss and other serious side effects.
Taking too much Albendazole can cause hair loss and other serious side effects.
September 2024 in “Meditsinskiy sovet = Medical Council” This article reports a rare case of toxic keratitis in a patient due to excessive intake of vitamin A, highlighting hypervitaminosis A risks such as severe eye conditions and systemic health issues, especially with cumulative doses exceeding therapeutic levels.