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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

New compounds may soon be tested to treat excessive hair growth in women.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Men with male pattern baldness have a higher risk of dying from prostate cancer.

A woman's liver problems improved after she stopped taking spironolactone.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Finasteride does not prevent bladder cancer.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.