30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
23 citations
,
July 2012 in “Calcified Tissue International” In this study, a single dose of PTH–CBD produced a sustained increase in bone mineral density for up to a year in mice, indicating its potential as an osteoporosis treatment.
22 citations
,
October 2011 in “Bone” This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.
19 citations
,
July 2015 in “Journal of inherited metabolic disease” This study observed that while betaine supplementation decreases total homocysteine and increases methionine levels in a mouse model of CBS deficiency, it is not as effective as methionine restriction in reversing associated phenotypes.
16 citations
,
March 2019 in “Actas Dermo-Sifiliográficas” This review discusses the relationship between vitamin D and various skin diseases but reports no new clinical results, emphasizing the need to assess and correct vitamin D deficiencies.
14 citations
,
November 2015 in “Annals of the New York Academy of Sciences” This review discusses dietary manipulation strategies in a mouse model of CBS deficiency and reports no new results; the authors emphasize the importance of understanding gene-diet interactions.
14 citations
,
February 2013 in “PubMed” This study found that 50% of patients with patchy alopecia areata who underwent chronic intralesional triamcinolone acetonide therapy had abnormal bone mineral density, suggesting the need for monitoring and preventive measures.
14 citations
,
April 2007 in “Journal of aging and health” This study observed that balding was associated with lower total body BMD in men and higher hip BMD in women, possibly due to estrogen use in the latter group.
14 citations
,
December 2017 in “Journal of Bone and Mineral Metabolism” This study found that women with polycystic ovary syndrome had a higher risk of fractures, including osteoporotic and specific types like spine and forearm fractures, compared to those without the condition.
12 citations
,
July 2016 in “Journal of dermatology” This study found that intramuscular triamcinolone acetonide may be an effective and safe treatment option for managing refractory alopecia areata, showing a 63% response rate in patients and hair regrowth negatively correlated with initial scalp involvement.
11 citations
,
November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.
9 citations
,
November 2014 in “Indian Journal of Endocrinology and Metabolism” This case report describes a young female with a rare combination of 46,XX gonadal dysgenesis and MRKH syndrome, highlighting associated infertility challenges.
8 citations
,
March 2008 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” This case study found that in a male-to-female transgender individual, long-term cyproterone use led to decreased bone mass, which improved with additional oestradiol treatment, highlighting the anabolic role of oestrogens on bone health.
6 citations
,
May 2022 in “Aging” This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.
5 citations
,
October 2003 in “PubMed” This case report describes a 30-year-old male with a late diagnosis of Kallmann's syndrome, highlighting the necessity of hormonal therapy to reduce the risk of osteoporosis and bone fractures despite the patient's acceptance of his physical appearance.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
4 citations
,
March 2013 in “Neuropsychiatric Disease and Treatment” This case report describes a rare instance of a patient with anorexia nervosa who was subsequently diagnosed with Cushing's syndrome, highlighting diagnostic challenges due to overlapping symptoms.
3 citations
,
January 2007 in “Elsevier eBooks” The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
1 citations
,
November 2022 in “Journal of the Endocrine Society” This study found that US adults with classic congenital adrenal hyperplasia most preferred a hypothetical adjunctive therapy that prevents glucocorticoid-induced weight gain over other potential benefits.
1 citations
,
January 2018 in “Side effects of drugs annual” This review in SEDA Volume 40 summarizes new adverse reaction data for diuretics published in 2017, highlighting specific risks such as fractures with loop diuretics and hyperkalemia with spironolactone.
1 citations
,
September 2016 in “Actas Dermo-Sifiliográficas” 5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
1 citations
,
April 2016 in “Journal of Investigative Dermatology” Patients with Focal Dermal Hypoplasia often experience skin, nail, hair, and bone issues, and may benefit from calcium and vitamin D supplements.
October 2025 in “Journal of the Endocrine Society” This report highlights that Klinefelter syndrome is often underdiagnosed due to phenotypic variability and emphasizes the importance of thorough physical examinations to improve diagnostic timing.
June 2025 in “British Journal of Dermatology” In this case report, a 67-year-old woman experienced patchy hair loss, likely related to denosumab treatment for osteoporosis, as other potential causes were ruled out; stopping denosumab led to hair regrowth following intralesional triamcinolone treatment, suggesting a potential denosumab-induced alopecia areata.
November 2023 in “Journal of the American Society of Nephrology” This report discusses two cases of kidney transplantation in transgender patients and highlights the complexities of managing gender-affirming care alongside post-transplantation health, including hormone therapy and associated risks.
September 2023 in “Physiology and Pharmacology” This review provides an overview of various animal models used to study glucocorticoid-induced humanlike disorders, highlighting their utility in understanding side effects across multiple body systems, such as hypertension, osteoporosis, and depression-like behavior.
December 2022 in “Journal of The American Academy of Dermatology” The authors maintain there is a significant link between vitamin D deficiency and central centrifugal cicatricial alopecia in Black patients, and call for more research on the topic.
August 2021 in “Annals of Agricultural and Environmental Medicine” This review provides a detailed analysis of frontal fibrosing alopecia, focusing on its prevalence in postmenopausal Caucasian women, associated comorbidities, and potential autoimmune, genetic, hormonal, and environmental factors; it emphasizes the need for improved understanding to enhance diagnosis and treatment.
April 2021 in “IntechOpen eBooks” This article discusses the need to investigate long-term effects of androgen manipulations independently of current levels, referencing Post-finasteride Syndrome as a relevant clinical example, and reports no new results.
May 2019 in “Cytotherapy” This study explored how Australian patients and their carers perceived autologous stem cell interventions, highlighting factors like illness experience and unrealistic expectations that influenced their decision-making in an unregulated market.