A Cross-Sectional Study Evaluating Skin, Hair, Nail, and Bone Disease in Patients with Focal Dermal Hypoplasia

April 2016 in “ Journal of Investigative Dermatology ”

N. Gunasekera, J DiVito, T.S. Kupper, J Huang, S Divito, N. Gunasekera, J DiVito, T.S. Kupper, J Huang, S Divito

Focal Dermal Hypoplasia skin disease scalp issues hair issues nail involvement papillomas bone disease osteoporosis calcium supplementation vitamin D supplementation bone density studies

TLDR Patients with Focal Dermal Hypoplasia often experience skin, nail, hair, and bone issues, and may benefit from calcium and vitamin D supplements.

This cross-sectional study investigated the prevalence and progression of skin, hair, nail, and bone disease in patients with Focal Dermal Hypoplasia (FDH) by surveying 17 participants at a conference. All participants reported skin and nail involvement, with 12 experiencing scalp/hair issues. Common triggers for skin flares included illness, weather changes, stress, and exercise. Notably, 11 participants observed skin disease progression, with 9 developing new papillomas. Bone issues were also reported, with 3 children experiencing multiple fractures and 1 confirmed case of osteoporosis. The study suggested that clinicians should counsel patients on potential disease progression and consider calcium and vitamin D supplementation, as well as bone density studies. It also emphasized the need for dermatologists to conduct thorough reviews and refer patients to specialists as needed.

View this study on jidonline.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 20 results

community Fin + Minoxidil + RU + Tretinoin + Castor Oil + Microneedling - 3 months. Opinions?

in Update 25 upvotes 4 years ago

The conversation discusses hair regrowth using finasteride, minoxidil, RU58841, tretinoin, castor oil, and microneedling over three months. There are signs of early hair regrowth, with expectations of fuller hair in a year.

community Hiding Baldness with Side Hair Growth

in Styling 145 upvotes 2 years ago

User hides baldness with side hair growth, others suggest it looks good but may not work in all conditions. Some recommend starting treatment or considering a hair transplant.

community Results after more than 1.5 years on Finasteride

in Finasteride/Dutasteride 243 upvotes 1 year ago

A user shared their experience with finasteride for hair loss, noting it slowed but didn't stop their hair loss, and they quit after 1.5 years. Suggestions included trying dutasteride, adding minoxidil, and maintaining a healthy lifestyle.

community 90days progress so far on 5% topical minoxidil 2x/day, 1.5mm dermaroll 1x/week, 1mg oral finasteride 1x/day

in Progress Pictures 584 upvotes 2 years ago

The conclusion of this conversation is that after 90 days of using 5% topical minoxidil, dermarolling once a week, and taking 1mg of oral finasteride daily, the user "M3ga_Shniz" has experienced a complete stop in hair loss thanks to finasteride. They are hopeful that their temples will continue to grow more as they continue with the treatment.

community Feeling really down and hair loss is slowly destroying me

in Chat 83 upvotes 5 years ago

The conversation is about a person struggling with aggressive hair loss and feeling depressed, who has tried finasteride but is experiencing sexual side effects. Others suggest various treatments like reducing finasteride dosage, trying minoxidil, dermarolling, addressing health and hormonal issues, and accepting baldness.

community I was a non-responder to Minoxidil before my esophagus surgery

in Research/Science 38 upvotes 1 year ago

The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

Related Research

2 / 2 results

research Serum Zinc Concentration in Patients With Alopecia Areata

October 2023 in “Acta dermato-venereologica (Print)”

People with severe hair loss have lower zinc levels in their blood.

research Alopecia Areata and Habit Tic Deformities

3 citations , January 2018 in “Skin Appendage Disorders”

Nail issues are common in alopecia areata patients.